Allele Dmel\JIL-1^{ΔCTD.Scer\UAS.T:Avic\GFP-ECFP}

General Information
Symbol	Dmel\JIL-1^{ΔCTD.Scer\UAS.T:Avic\GFP-ECFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0270114
Feature type	allele	Associated gene	Dmel\JIL-1

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion, in vitro construct - deletion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Wang et al., 2011) in vitro construct - deletion (Wang et al., 2011) in vitro construct - regulatory fusion (Wang et al., 2011)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of JIL-1 sequences with the C-terminal domain removed (leaving 1-926) tagged at the C-terminus with T:Avic\GFP[ECFP]. (Wang et al., 2011)
Carried in construct	P{UAS-JIL-1.ΔCTD-CFP} (Wang et al., 2011)
Tagged with	T:Avic\GFP^ECFP (Wang et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	enhancer of variegation, with In(1)w^m4, Scer\GAL4^da.G32 (Wang et al., 2011) suppressor of variegation, with JIL-1^z2, Scer\GAL4^da.G32, w^118E-10 (Wang et al., 2011) suppressor of variegation (with JIL-1^z2), with Scer\GAL4^da.G32, w^118E-10 (Wang et al., 2011)
Phenotype Manifest In

Detailed Description
	Statement Reference Expression of JIL-1[ΔCTD.Scer\UAS.T:Avic\GFP-ECFP] under the control of Scer\GAL4[da.G32] suppresses position effect variegation in In(1)w[m4] flies, as indicated by the increased proportion of red ommatidia and a 348% increase in the optical density of eye pigment levels, when compared to controls. Expression of JIL-1[ΔCTD.Scer\UAS.T:Avic\GFP-ECFP] in a JIL-1[z2]; w[118E-10]/+ mutant background, under the control of Scer\GAL4[da.G32], suppresses the position effect variegation seen in the eye, as indicated by an increases in the proportion of red ommatidia and a statistically significant 151% increase in the optical density of eye pigment levels. (Wang et al., 2011)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	JIL-1^{ΔCTD.Scer\UAS.T:Avic\GFP-ECFP}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Wang et al., 2011, J. Cell Sci. 124(24): 4309--4317 The epigenetic H3S10 phosphorylation mark is required for counteracting heterochromatic spreading and gene silencing in Drosophila melanogaster. [FBrf0217232]

Allele Dmel\JIL-1ΔCTD.Scer\UAS.T:Avic\GFP-ECFP

Allele Dmel\JIL-1^{ΔCTD.Scer\UAS.T:Avic\GFP-ECFP}