Imprecise excision of P{RS3}AcerCB-0338-3 generates a 329bp deletion within Acer.
329 bp deletion resulting from the imprecise excision of P{RS3}AcerCB-0338-3, which removes most of the 5' UTR and the first 12 codons of Acer.
AcerΔ164 mutant males that have been entrained in a 12h light-dark cycle are two- to threefold more active than control flies during the night-time period (from midnight to 6am) but not during the day-time quiescent period (12-6pm). The locomotor activity of these flies during wakeful episodes is no greater than wild-type controls. AcerΔ164 females also display higher locomotor activity during the night-time period compared to controls.
AcerΔ164 mutants sleep around 15% less during the hours of darkness compared with wild-type flies. The longest period of sleep for AcerΔ164 mutants is shortened by around 50% and the number of sleep episodes experienced by AcerΔ164 mutants is increased by 60%, compared to controls. Thus, these flies sleep less during the hours of darkness and have more fragmented night-time sleep.
