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General Information
Symbol
Dmel\tkvUbi-p63E.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0270122
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 2.0kb Ubi-p63E promoter fragment drives expression of a full-length tkv coding region tagged at the C-terminal end with Tag:HA. The Ubi-p63E promoter contains 660bp upstream of Ubi-p63E and the 5' portion of Ubi-p63E.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The presence of tkvUbi-p63E.T:Ivir\HA1 in a wild-type background results in the L2 wing vein appearing slightly closer to the anterior-posterior boundary compared to controls.

Adult wings from flies carrying tkvUbi-p63E.T:Ivir\HA1 appear relatively normal with respect to wing pattern and size, with the exception that the distal region is more pointed than in wild-type and a portion of a vein is missing. The position of the L2 wing vein is significantly closer to the anterior-posterior boundary in tkvUbi-p63E.T:Ivir\HA1 flies compared to wild-type imaginal discs. Increasing the tkvUbi-p63E.T:Ivir\HA1 copy number does not alter the position of the L2 wing vein.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

tkvUbi-p63E.Tag:HA is a suppressor of wing vein L2 phenotype of Dad212

Additional Comments
Genetic Interactions
Statement
Reference

The position of the L2 wing vein in Dad212 moves towards the anterior-posterior boundary as the copy number of tkvUbi-p63E.T:Ivir\HA1 increases.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
tkvUbi-p63E.T:Ivir\HA1
tkvUbi-p63E.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)