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General Information
Symbol
Dmel\AckUAS.cSb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Schoenherr
FlyBase ID
FBal0270230
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of wild-type Ack.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing one copy of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU have slightly larger eyes than normal, while flies expressing two copies of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU have a highly disorganised eye.

Expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU results in an increase in the number of interommatidial bristles without significantly affecting the number of pigment cells when assessed at 42% pupa development.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU greatly suppresses the reduced eye size caused by WGMR.PG.

Expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU suppresses the reduced eye size caused by rprGMR.PH.

Co-expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU suppresses the increased number of apoptotic cells seen posterior to the second mitotic wave and in the posterior region of the eye disc in the zone of compensatory proliferation in eye discs expressing WGMR.PG.

Expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU suppresses the small eye phenotype caused by WAla5.GMR. Further suppression is seen if the flies are also heterozygous for either aosΔ7/+ or Gap1mip-w+/+.

Animals expressing AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU in a aosΔ7/+ or Gap1mip-w+/+ background show a 25% increase in pigment cell number when assessed at 42% pupa development.

Expression of AckScer\UAS.cSb under the control of Scer\GAL4GMR.PU suppresses the small eye phenotype caused by WAla5.GMR. Further suppression is seen if the flies are also co-expressing SH3PX1KK100618.

Co-expression of either Hsp26KK106347 or MagiGD10066 further reduces the size of the eye in a WAla5.GMR, AckScer\UAS.cSb, Scer\GAL4GMR.PU background.

Co-expression of drkKK109233 in a WAla5.GMR, AckScer\UAS.cSb, Scer\GAL4GMR.PU background results in flies with eyes that are greatly reduced in size.

Co-expression of AckScer\UAS.cSb and ykiScer\UAS.cHa under the control of Scer\GAL4GMR.PU results in a massively overgrown eye.Co-expression of AckScer\UAS.cSb and ykiScer\UAS.cHa under the control of Scer\GAL4GMR.PU results in a massively overgrown eye.

Xenogenetic Interactions
Statement
Reference

Co-expression of AckScer\UAS.cSb and Hsap\YAP1S94A.S127A.Scer\UAS under the control of Scer\GAL4GMR.PU results in an increased eye size.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
AckScer\UAS.cSb
AckUAS.cSb
Name Synonyms
Saccharomyces cerevisiae UAS construct b of Schoenherr
Secondary FlyBase IDs
    References (1)