FlyBase Allele Report: Dmel\wg[NIG.4889R]

General Information

Symbol

Dmel\wg^NIG.4889R

Species

D. melanogaster

Name

FlyBase ID

FBal0274420

Feature type

allele

Associated gene

Dmel\wg

Associated Insertion(s)

Carried in Construct

P{NIG.4889R}

Also Known As

4889R, UAS-wg RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.4889R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-4889R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

egg chamber, with Scer\GAL4^hs.PU

(Wang and Page-McCaw, 2014)

Detailed Description

Statement

Reference

Expression of wg^NIG.4889R under the control of Scer\GAL4^hs.PU results in fused egg chambers (60% penetrance).

(Wang and Page-McCaw, 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^ptc-559.1/wg^NIG.4889R is a suppressor | partially of abnormal cell migration | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, scrib^GD11666

(Zhang et al., 2019)

Scer\GAL4^ptc-559.1/wg^NIG.4889R is a suppressor of visible phenotype of Scer\GAL4^ptc-559.1, puc^RNAi.UAS.cUa

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of abnormal size phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of abnormal size phenotype of Scer\GAL4^GMR.PF, hep^CA.UAS

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, hep^CA.UAS

(Zhang et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^ptc-559.1/wg^NIG.4889R is a suppressor | partially of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Scer\GAL4^ptc-559.1, scrib^GD11666

(Zhang et al., 2019)

Scer\GAL4^ptc-559.1/wg^NIG.4889R is a suppressor of anterior crossvein phenotype of Scer\GAL4^ptc-559.1, puc^RNAi.UAS.cUa

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Zhang et al., 2015)

wg^NIG.4889R/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, hep^CA.UAS

(Zhang et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

4889R-3

P{NIG.4889R}3

4889R-4

P{NIG.4889R}4

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

wg^NIG.4889R

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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