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General Information
Symbol
Dmel\me31BNIG.4916R
Species
D. melanogaster
Name
FlyBase ID
FBal0274435
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a 500bp inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of me31BNIG.4916R (together with UAS-Dicer2 to enhance RNAi efficiency) under the control of Scer\GAL4tim.PE results in poor rhythmicity of adult circadian locomotor activity under free-running (~constant darkness, DD) conditions and while the daily oscillation of per and tim proteins (under standard light-dark conditions) are not perturbed, the oscillation of the Pdf protein in the axons of s-LNv neurons is abolished.

Poor locomotor behavior rhythmicity in DD conditions is also observed when the me31BNIG.4916R is driven by either Scer\GAL4P2.4.Pdf or Scer\GAL4cry.PE.

Expression of me31BNIG.4916R under the control of Scer\GAL4GH146 completely blocks the long-term habituation (LTH) seen when flies are exposed to ethyl butyrate (EB) for 4 days.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
NOT Enhancer of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The poor rhythmicity of adult circadian locomotor activity under free-running (~constant darkness) conditions observed in flies expressing me31BNIG.4916R under the control of Scer\GAL4cry.PE is further worsened by co-expression of Atx2KK100423.

The aberrant long-period circadian locomotor rhythm under free-running constant dark conditions characteristic for adult flies expressing tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4Mz520 is not enhanced by co-expression of me31BNIG.4916R.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
me31BNIG.4916R
Name Synonyms
Secondary FlyBase IDs
    References (4)