FlyBase Allele Report: Dmel\Usp47[NIG.5486R]

General Information

Symbol

Dmel\Usp47^NIG.5486R

Species

D. melanogaster

Name

FlyBase ID

FBal0274703

Feature type

allele

Associated gene

Dmel\Usp47

Associated Insertion(s)

Carried in Construct

P{NIG.5486R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.5486R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-5486R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Flies expressing Ubp64E^NIG.5486R via Scer\GAL4^Act5C.PI that are fed with paraquat do not live longer than controls fed with paraquat.

(Bingol et al., 2014)

Expression of Ubp64E^NIG.5486R under the control of Scer\GAL4^bbg-C96 does not result in a wing phenotype.

Expression of Ubp64E^NIG.5486R under the control of Scer\GAL4^dpp.PU does not result in a bristle phenotype.

(Zhang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^salm.EPv/Usp47^NIG.5486R is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^salm.EPv, rl^Sem.S.UAS

(Ashton-Beaucage et al., 2016)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^salm.EPv/Usp47^NIG.5486R is a suppressor | partially of wing blade phenotype of Scer\GAL4^salm.EPv, rl^Sem.S.UAS

(Ashton-Beaucage et al., 2016)

Scer\GAL4^salm.EPv/Usp47^NIG.5486R is a suppressor | partially of wing vein | ectopic phenotype of Scer\GAL4^salm.EPv, rl^Sem.S.UAS

(Ashton-Beaucage et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

The formation of ectopic wein material in the adult wing characteristic for flies expressing rl^{Sem.S.Scer\UAS} under the control of Scer\GAL4^salm.EPv is partially suppressed by co-expression of either Usp47^GD10642 or Usp47^NIG.5486R. The ameliorated phenotype of Scer\GAL4^salm.EPv,rl^{Sem.S.Scer\UAS};Usp47^GD10642 flies can be worsened again by co-expression of either poe^GD8339 or poe^KK101471 : the severity of their ectopic venation phenotype is comparable to that of flies expressing rl^{Sem.S.Scer\UAS} only.

(Ashton-Beaucage et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

5486R-3

P{NIG.5486R}3

5486R-4

P{NIG.5486R}4

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ubp64E^NIG.5486R

Usp47^NIG.5486R

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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