FB2025_01 , released February 20, 2025
Allele: Ecol\lexAGr66a.PS
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General Information
Symbol
Ecol\lexAGr66a.PS
Species
E. coli
Name
Gustatory receptor 66a promoter construct of Scott
FlyBase ID
FBal0277069
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{Gr66a-lexA.S}
Also Known As
Gr66a-LexA, Gr66a-LexA::VP16
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Thistle et al., 2012)
Progenitor genotype
Carried in construct
P{Gr66a-lexA.S}
Cytology
Description

Gr66a regulatory sequences regulate expression of a lexA::UnkAD driver.

(Thistle et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
Gr66a
Encoded product / tool
lexA::UnkAD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory system neuron | subset of terminal organ
      (Croset et al., 2016)
      larval gnathal ganglion | restricted
      (Croset et al., 2016)
      bitter-sensing neuron
      (Ahn and Amrein, 2023)
      adult stage
      bitter-sensing neuron
      (Deere et al., 2023)
      high salt/bitter-sensing neuron
      (Sánchez-Alcañiz et al., 2018)
      Additional Information
      Statement
      Reference

      Ecol\lexAGr66a.PS drives expression in bitter-sensing neurons of larval external sensory organs, including those of the terminal organ and dorsal organ; and of interior sense organs including those of the dorsopharyngeal organ and hypopharyngeal organ.

      (Ahn and Amrein, 2023)

      Drives expression in bitter-sensing neurons in larval and adult gustatory receptors.

      (FlyBase Curators, 2017)
       
      Marker for
      bitter-sensing neuron
      (Deere et al., 2023)
      Reflects expression of
      Gr66a
      (Ahn and Amrein, 2023, Deere et al., 2023, Sánchez-Alcañiz et al., 2018)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Ecol\lexAGr66a.PS
      Ecol\lexAGr66a.PU
      Ecol\lexAGr66a
      Gr66a-LexA
      (Mann et al., 2013)
      Gr66aLexa
      (Masuzzo et al., 2022)
      Name Synonyms
      Gustatory receptor 66a promoter construct of Scott
      Secondary FlyBase IDs
        References (27)