FlyBase Allele Report: Dmel\cv-d[UAS.Tag:V5]

General Information

Symbol

Dmel\cv-d^UAS.Tag:V5

Species

D. melanogaster

Name

FlyBase ID

FBal0277149

Feature type

allele

Associated gene

Dmel\cv-d

Associated Insertion(s)

Carried in Construct

P{UAS-cv-d.V5}

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Chen et al., 2012)

in vitro construct - coding region fusion

(Chen et al., 2012)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-cv-d.V5}

Cytology

Nature of the lesion

Statement

Reference

UAS drives expression of cv-d cDNA tagged at the C-terminus with Tag:V5.

(Chen et al., 2012)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

cv-d

Tagged with

Tag:V5

epitope tag

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

wing margin, with Scer\GAL4^hh.PU

(Chen et al., 2012)

wing margin, with Scer\GAL4^nub-AC-62

(Chen et al., 2012)

Detailed Description

Statement

Reference

Over-expression of cv-d^{Scer\UAS.T:SV5\V5} does not induce ectopic veins in the wing. The only external defect seen when Scer\GAL4^hh.PU or Scer\GAL4^nub-AC-62 drives cv-d^{Scer\UAS.T:SV5\V5} expression is scalloping of the wing margin.

(Chen et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

cv-d^UAS.Tag:V5/Scer\GAL4^Tub.PU rescues cv-d¹³

(Chen et al., 2012)

cv-d^UAS.Tag:V5/Scer\GAL4^Tub.PU rescues cv-d¹

(Chen et al., 2012)

cv-d^UAS.Tag:V5/Scer\GAL4^Hml.PG rescues cv-d¹

(Chen et al., 2012)

cv-d^UAS.Tag:V5/Scer\GAL4^unspecified rescues cv-d¹³

(Chen et al., 2012)

Comments

Scer\GAL4^tub.PU-mediated expression of cv-d^{Scer\UAS.T:SV5\V5} results in complete rescue of the cv-d¹³ posterior crossvein phenotype.

(Chen et al., 2012)

Scer\GAL4^tub.PU- or Scer\GAL4^Hml.PG-mediated expression of cv-d^{Scer\UAS.T:SV5\V5} rescues posterior crossvein development in cv-d¹ mutants. Scer\GAL4^unspecified-mediated expression of cv-d^{Scer\UAS.T:SV5\V5} rescues posterior crossvein development in cv-d¹³ mutants.

(Chen et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

42668

w^*; P{UAS-cv-d.V5}3/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

cv-d^{Scer\UAS.T:SV5\V5}

cv-d^UAS.Tag:V5

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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