Eggs laid by homozygous females show a very low rate of hatching (0.2%). Most embryos laid by the mutant females show normal nuclear morphology until division 12, but by division 13-14, less than one-third of the mutant embryos have normal nuclear morphology.
Homozygous animals do not show an increased frequency of generation of mutant clones compared to wild type in a loss of heterozygosity assay.
Ionising radiation-induced G2 arrest and apoptosis occur normally in homozygous eye discs.
Homozygous eye discs show defects in hydroxyurea-induced G2 arrest.
Homozygous larvae show reduced survival in the presence of hydroxyurea compared to wild type.