|Name||Saccharomyces cerevisiae UAS construct a of Kim||FlyBase ID||FBal0277251|
|Feature type||allele||Associated gene||Dmel\psidin|
|Mutagen||in vitro construct - regulatory fusion|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Carried in construct|
|Phenotype Manifest In|
Border follicle cells expressing psidin[Scer\UAS.cKa] under the control of Scer\GAL4[slbo.2.6] at 29[o]C have longer actin-rich protrusions than control cells. The protrusions are highly irregular in morphology, as they are elongated, irregular in length, of variable thickness and can even be branched.
|Phenotype Manifest In|
Co-expression of Act5C[slbo.T:Avic\GFP-EGFP] and of psidin[Scer\UAS.cKa] under the control of Scer\GAL4[slbo.2.6] results in a strong inhibition of border follicle cell migration. Expression of psidin[Scer\UAS.cKa] under the control of Scer\GAL4[slbo.2.6] in a tsr, ssh[1-63], WASp, Hem[J4-48] or zip heterozygous background has little or no effect on border cell migration. Expression of psidin[Scer\UAS.cKa] under the control of Scer\GAL4[slbo.2.6] in a Rac1[J11] Rac2[Δ] double heterozygous background has little or no effect on border cell migration.
|Complementation & Rescue Data|
Expression of psidin[Scer\UAS.cKa] under the control of Scer\GAL4[slbo.2.6] rescues the migration defects seen in homozygous psidin[55D4] border cells. Expression of psidin[Scer\UAS.cKa] under the control of Scer\GAL4[Act.PU] rescues the lethality of psidin[55D4]/psidin[85D1] animals.
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 2 )|
Saccharomyces cerevisiae UAS construct a of Kim
|Secondary FlyBase IDs|
|References ( 1 )|