Allele Dmel\PGRP-LC^LCy

General Information
Symbol	Dmel\PGRP-LC^LCy	Species	D. melanogaster
Name		FlyBase ID	FBal0277276
Feature type	allele	Associated gene	Dmel\PGRP-LC

Allele class
Mutagen	in vitro construct
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct (Neyen et al., 2012)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Encodes the "LCy" isoform of PGRP-LC, which is comprised of the sequence fragments 3L:9330982..9338167, 3L:9339691..9340742 and 3L:9341277..9342747 (release 5 genome coordinates). (Neyen et al., 2012)
Carried in construct	M{PGRP-LCy.PGRP-LF} (Neyen et al., 2012)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	PGRP-LC^LCa/PGRP-LC^LCy fails to rescue PGRP-LC^ΔE/PGRP-LC^ΔE (Neyen et al., 2012) PGRP-LC^LCy fails to rescue PGRP-LC^ΔE/PGRP-LC^ΔE (Neyen et al., 2012)
Comments	PGRP-LC[LCy] fails to rescue the susceptibility of PGRP-LC[ΔE] flies to infection with Erwinia carotovora carotovora by septic injury. PGRP-LC[LCa] and PGRP-LC[LCy] in combination fail to rescue the susceptibility of PGRP-LC[ΔE] flies to infection with Erwinia carotovora carotovora by septic injury. (Neyen et al., 2012)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	PGRP-LC^LCy
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Neyen et al., 2012, J. Immunol. 189(4): 1886--1897 Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE. [FBrf0219094]

Allele Dmel\PGRP-LCLCy

Allele Dmel\PGRP-LC^LCy