FB2025_01 , released February 20, 2025
Allele: Dmel\mir-311UAS.pLUC
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General Information
Symbol
Dmel\mir-311UAS.pLUC
Species
D. melanogaster
Name
FlyBase ID
FBal0277355
Feature type
allele
Associated gene
Dmel\mir-311
Associated Insertion(s)
Carried in Construct
P{UAS-LUC-mir-311.T}
Key Links
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
in vitro construct
(Bejarano et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-LUC-mir-311.T}
Cytology
Description

UAS regulatory sequences drive expression of Ppyr\LUC followed by a genomic fragment containing the mir-311 pre-miRNA hairpin.

(Bejarano et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-311
Tagged with
pLUC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult escapers expressing mir-311Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4Bx-MS1096 are all female. The wings are curved and the veins are slightly thicker than normal.

      Expression of mir-311Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4sd-SG29.1 results in curved wings.

      Expression of mir-311Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4ptc-559.1 results in a reduction in the space between veins L3 and L4 and hairs are missing.

      (Bejarano et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Scer\GAL4L4/mir-311UAS.pLUC is an enhancer of chemical sensitive | dominant phenotype of esgL4

      (Sanchez-Díaz et al., 2015)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Scer\GAL4L4/mir-311UAS.pLUC is an enhancer of abdomen phenotype of esgL4

      (Sanchez-Díaz et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of mir-311Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4L4 enhances the cuticle phenotype seen in esgL4/+ mutant flies, with 23% of the resulting flies having phenotypes compared with 8% in esgL4/+ alone. Viability is unaffected. The increase in nicotine sensitivity is also enhanced.

      (Sanchez-Díaz et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mir-311Scer\UAS.T:Ppyr\LUC
      mir-311UAS.pLUC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)