FlyBase Allele Report: Dmel\mir-bft[UAS.DsRed(Unk)]

General Information

Symbol

Dmel\mir-bft^{UAS.DsRed(Unk)}

Species

D. melanogaster

Name

FlyBase ID

FBal0278019

Feature type

allele

Associated gene

Dmel\mir-bft

Associated Insertion(s)

Carried in Construct

P{UAS-DsRed-mir-bft.L}

Key Links

Transgenic product class

wild_type

(Bejarano et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Bejarano et al., 2012)

Mutagen

in vitro construct

(Bejarano et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-DsRed-mir-bft.L}

Cytology

Description

UAS regulatory sequences drive expression of a DsRed(Unk) fluorescent protein. A genomic fragment containing the bft pre-miRNA hairpin has been inserted into the DsRed(Unk) 3'UTR.

(Bejarano et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mir-bft

Tagged with

DsRed(Unk)

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cystic fibrosis

modeled by Cftr^NIG.5789R

(Kim et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^da.G32

(Bejarano et al., 2012)

lethal - all die before end of P-stage, with Scer\GAL4^ptc-559.1

(Bejarano et al., 2012)

some die during pharate adult stage, with Scer\GAL4^ptc-559.1

(Bejarano et al., 2012)

visible, with Scer\GAL4^Bx-MS1096

(Bejarano et al., 2012)

visible, with Scer\GAL4^sd-SG29.1

(Bejarano et al., 2012)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Bejarano et al., 2012, Bejarano et al., 2012)

wing, with Scer\GAL4^sd-SG29.1

(Bejarano et al., 2012)

Detailed Description

Statement

Reference

Expression of bft^{Scer\UAS.T:Disc\RFP} under the control of Scer\GAL4^sd-SG29.1 results in wings which consist of a hairy blister with no vein pattern.

(Bejarano et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

mir-bft^{UAS.DsRed(Unk)}, Scer\GAL4^Act5C.PP is a suppressor of increased cell size | adult stage phenotype of Cftr^NIG.5789R, Scer\GAL4^Act5C.PP

(Kim et al., 2020)

mir-bft^{UAS.DsRed(Unk)}, Scer\GAL4^Myo31DF.PU is a suppressor | partially of increased occurrence of cell division | adult stage phenotype of Cftr^NIG.5789R, Scer\GAL4^Myo31DF.PU

(Kim et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

mir-bft^{UAS.DsRed(Unk)}, Scer\GAL4^Act5C.PP is a suppressor of enterocyte of anterior adult midgut epithelium | somatic clone | adult stage phenotype of Cftr^NIG.5789R, Scer\GAL4^Act5C.PP

(Kim et al., 2020)

mir-bft^{UAS.DsRed(Unk)}, Scer\GAL4^Myo31DF.PU is a suppressor | partially of adult midgut epithelium phenotype of Cftr^NIG.5789R, Scer\GAL4^Myo31DF.PU

(Kim et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

bft^{Scer\UAS.T:Disc\RFP}

bft^{UAS.DsRed(Unk)}

mir-bft^{UAS.DsRed(Unk)}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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