FB2025_01 , released February 20, 2025
Allele: Scer\GAL4insc-Mz1407
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General Information
Symbol
Scer\GAL4insc-Mz1407
Species
S. cerevisiae
Name
FlyBase ID
FBal0278258
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
insc-gal4, 1407-Gal4, inscGAL4, inscuteable-Gal4, GAL4-1407, 1407, MZ1407, Gal41407, MZ1407-Gal4, GAL4MZ1407
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Inserted element
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression most segregating embryonic neuroblasts and their progeny, but not in the neurectoderm; in neuroblasts of the larval optic lobe, central brain, and ventral nerve cord, but not the neuroepithelial cells of the outer optic anlage (OPC).

ScerGAL4insc-Mz1407 drives expression in proximal parts of neuroblast lineages up to and including young Kenyon cells, but not mature Kenyon cells. Expression overlaps with dpn positive mushroom body neuroblasts and Rx positive ganglion mother cells and young Kenyon cells and with dac in some Kenyon cells at the late third instar larval stage.

ScerGAL4insc-Mz1407 drives expression in neuroblasts of the larval optic lobe, central brain, and ventral nerve cord, but not the neuroepithelial cells of the outer optic anlage (OPC).

Expression is observed throughout the nervous system during embryogenesis, but ceases after hatching.

In embryo, expressed in most segregated neuroblasts and their progeny, but not in the neurectoderm.

In embryo, expressed in many segregating neuroblasts and their progeny; is not expressed in the ventral midline.

Pan-neural expression in the embryo: in all peripheral sensory neurons, cell bodies of the CNS, afferent and efferent axons in the peripheral nerves and in individual boutons of the neuromuscular junction.

 
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

larval brain | posterior & neuroblast | supernumerary, with aPKCΔN.UAS

sensory neuron & labellar taste bristle, with GαsRNAi.UAS

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
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NOT Enhanced by
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Suppressed by
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NOT suppressed by
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Enhancer of
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NOT Enhancer of
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Suppressor of
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NOT Suppressor of
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Phenotype Manifest In
Enhanced by
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NOT Enhanced by
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Suppressed by
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NOT suppressed by
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Enhancer of
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NOT Enhancer of
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Suppressor of
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NOT Suppressor of
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Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescues
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (12)
Reported As
Name Synonyms
Secondary FlyBase IDs
  • FBal0040458
  • FBal0086837
  • FBal0189683
References (240)