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General Information
Symbol
Dmel\Usp8HMS01898
Species
D. melanogaster
Name
FlyBase ID
FBal0279014
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of a short inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of Usp8HMS01898 under the control of Scer\GAL4Bx-MS1096 results in malformed adult wings.
Knockdown of Usp8HMS01898 driven in the class IV dendritic arborizing sensory neuron ddaC by Scer\GAL4ppk.1.9 leads to disruptions in pruning at 18hr after puparium formation, with dendrites still attached to the cell body (resulting from a lack of branch severing and clearance defects).
Flies expressing UbpyHMS01898 under the control of Scer\GAL4Dvir\Pdf.1.9 have a long locomotor activity period (1.3 hours longer than control flies).
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
The rough eye phenotype characteristic for adult flies expressing Hsap\SNCAScer\UAS.cFa under the control of Scer\GAL4GMR.PU is restored by co-expression of Usp8HMS01898. The rough eye phenotype, the age-progressive decrease in climbing abilities as well as the loss of neurons in the PPM1/2 cluster observed in adult flies expressing Hsap\SNCAA53T.Scer\UAS under the control of Scer\GAL4Ddc.HL9 is rescued by co-expression of Usp8HMS01898 RNAi. The rough eye phenotype characteristic for adult flies expressing either Hsap\ATXN3tr.Q78.Scer\UAS.T:Ivir\HA1 or Hsap\HTT128Q.FL.Scer\UAS under the control of Scer\GAL4GMR.PU is not suppressed by expression of Usp8HMS01898.
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
UbpyHMS01898
Usp8HMS01898
Name Synonyms
Secondary FlyBase IDs
    References (5)