FlyBase Allele Report: Dmel\tau[HMS02042]

General Information

Symbol

Dmel\tau^HMS02042

Species

D. melanogaster

Name

FlyBase ID

FBal0279154

Feature type

allele

Associated gene

Dmel\tau

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS02042}

Genomic Maps

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Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - RNAi

(Ni et al., 2010.12.1)

in vitro construct - regulatory fusion

(Ni et al., 2010.12.1)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{TRiP.HMS02042}

Cytology

Nature of the lesion

Statement

Reference

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tau

Also carries

loxP

recombinase target site

Associated Sequence Features

dsRNA-HMS02042

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

abnormal memory | adult stage, with Scer\GAL4^GMR13F02

(Papanikolopoulou et al., 2019)

abnormal pain response | adult stage, with Scer\GAL4^GMR13F02

(Papanikolopoulou et al., 2019)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of tau^HMS02042 under the control of Scer\GAL4^GMR13F02, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, significantly increases aversive olfactory 24 h memory following spaced training, compared to controls; there is also a significant failure to habituate to electric shocks, compared to controls.

(Papanikolopoulou et al., 2019)

Expression of tau^HMS02042 under the control of Scer\GAL4^ppk.PU, in combination with a Dicer-2 transgene to enhance RNAi efficiency, does not impair pruning of ddaC dendrites by 16 h after puparium formation (APF), compared to controls.

(Wang et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

tau^HMS02042, Scer\GAL4^ppk.PU is a non-enhancer of abnormal neuroanatomy | pupal stage phenotype of Patronin^KK100898, Scer\GAL4^ppk.PU

(Wang et al., 2019)

tau^HMS02042, Scer\GAL4^ppk.PU is a non-enhancer of abnormal cell shape | pupal stage phenotype of Patronin^KK100898, Scer\GAL4^ppk.PU