FB2025_01 , released February 20, 2025
Allele: Dmel\Trx26
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General Information
Symbol
Dmel\Trx26
Species
D. melanogaster
Name
FlyBase ID
FBal0279429
Feature type
allele
Associated gene
Dmel\Trx2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Svensson and Larsson, 2007)
Mutagen
Delta2-3 transposase
(Svensson and Larsson, 2007)
Progenitor genotype
P{GT1}Trx2BG02804
(Svensson and Larsson, 2007)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of Trx-2, corresponding to the last 30bp of the first exon, all of the second exon and part of the second intron.

(Svensson and Larsson, 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous flies have a small but significant reduction in lifespan compared to controls.

      (Svensson and Larsson, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Trx-26 Df(1)J5 flies show decreased tolerance to oxidative stress compared to controls.

      (Svensson and Larsson, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Trx26 is rescued by Trx2+tSa

      (Svensson and Larsson, 2007)
      Comments

      Trx-2+tSa rescues the shortened lifespan of Trx-26 homozygotes.

      (Svensson and Larsson, 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Trx-26
      (Svensson and Larsson, 2007)
      Trx26
      Name Synonyms
      Secondary FlyBase IDs
        References (1)