FlyBase Allele Report: Dmel\Wnk[HMJ02087]

General Information

Symbol

Dmel\Wnk^HMJ02087

Species

D. melanogaster

Name

FlyBase ID

FBal0281363

Feature type

allele

Associated gene

Dmel\Wnk

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ02087}

Also Known As

UAS-DmWNK^RNAi, Wnk-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ02087}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ02087

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^Bx-MS1096

(Yarikipati et al., 2023)

decreased size | adult stage, with Scer\GAL4^en.PU

(Yarikipati et al., 2023)

decreased size | larval stage, with Scer\GAL4^en.PU

(Yarikipati et al., 2023)

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

wing blade, with Scer\GAL4^Bx-MS1096

(Yarikipati et al., 2023)

wing blade posterior compartment, with Scer\GAL4^en.PU

(Yarikipati et al., 2023)

wing disc posterior compartment, with Scer\GAL4^en.PU

(Yarikipati et al., 2023)

wing hair, with Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Detailed Description

Statement

Reference

Females heterozygous for Wnk^HMJ02087 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to Wnk^HMJ02087 males results in: 78% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, non-enhanceable by fray^D185A.UAS/Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, non-enhanceable by Ncc69^r2/Ncc69^r2

(Yarikipati et al., 2023)

Suppressed by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, suppressible | partially by Rnor\Wnk1^UAS.3, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, suppressible by Scer\GAL4^en.PU/fray^UAS.cRa

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, suppressible by Hsap\WNK2^UAS.cSa, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, suppressible | partially by Mmus\Wnk4^UAS.cSa, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

NOT suppressed by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has decreased size | adult stage phenotype, non-suppressible by Ncc69^r2/Ncc69^r2

(Yarikipati et al., 2023)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, non-enhanceable by fray^D185A.UAS/Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing hair phenotype, non-enhanceable by fray^D185A.UAS/Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, non-enhanceable by Ncc69^r2/Ncc69^r2

(Yarikipati et al., 2023)

Suppressed by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, suppressible by Hsap\WNK2^UAS.cSa, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, suppressible | partially by Mmus\Wnk4^UAS.cSa, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, suppressible | partially by Rnor\Wnk1^UAS.3, Scer\GAL4^en.PU

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, suppressible by Scer\GAL4^en.PU/fray^UAS.cRa

(Yarikipati et al., 2023)

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing hair phenotype, suppressible by Scer\GAL4^en.PU/fray^UAS.cRa

(Yarikipati et al., 2023)

NOT suppressed by

Statement

Reference

Scer\GAL4^en.PU, Wnk^HMJ02087 has wing blade posterior compartment phenotype, non-suppressible by Ncc69^r2/Ncc69^r2

(Yarikipati et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Wnk^HMJ02087 is rescued by Scer\GAL4^en.PU/Wnk^UAS.cSa

(Yarikipati et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

42521

y¹ v¹; P{TRiP.HMJ02087}attP40

NIG-Fly

HMJ02087

y¹ v¹; P{TRiP.HMJ02087}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Wnk^HMJ02087

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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