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General Information
Symbol
Dmel\upd2Δ
Species
D. melanogaster
Name
FlyBase ID
FBal0283676
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
upd2Δ
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

4.7 kb deletion generated by FLP-mediated recombination between PBac{WH}f04435 and P{XP}d03621.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Scer\FLP1-mediated recombination between the two progenitor insertions has resulted in a 4.7kb deletion that removes the upd2 transcription unit.

Insertion components
P+PBac{XP5.WH5}upd2Δ
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutants do not show any major developmental defects.

The response of increased proliferation of intestinal stem cells which is seen in wild-type flies after oral infection with Erwinia carotovora carotovora 15 is reduced in mutant flies compared to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference

upd2Δ, upd2[+], upd3Δ, upd3[+] is a non-enhancer of visible | adult stage phenotype of CtBP334Δ4, Scer\GAL4rn-GAL4-5, egrUAS.cUa, upd1UAS.cUa

Suppressor of
NOT Suppressor of
Statement
Reference

upd2Δ, upd2[+], upd3Δ, upd3[+] is a non-suppressor of visible | adult stage phenotype of CtBP334Δ4, Scer\GAL4rn-GAL4-5, egrUAS.cUa, upd1UAS.cUa

Other
Phenotype Manifest In
NOT Enhancer of
Statement
Reference

upd2Δ, upd2[+], upd3Δ, upd3[+] is a non-enhancer of wing | ectopic phenotype of CtBP334Δ4, Scer\GAL4rn-GAL4-5, egrUAS.cUa, upd1UAS.cUa

Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

upd2Δ, upd2[+], upd3Δ, upd3[+] is a non-suppressor of wing | ectopic phenotype of CtBP334Δ4, Scer\GAL4rn-GAL4-5, egrUAS.cUa, upd1UAS.cUa

Additional Comments
Genetic Interactions
Statement
Reference

upd2Δupd3Δ double mutants show increased mortality as a result of WNV-Kun infection when compared to controls.

Expression of egrUAS.cUa under the control of Scer\GAL4rn-GAL4-5 (with tub-Gal80[ts] restricting expression to third instar larvae) in upd2Δ/+ or upd2Δ/+ upd3Δ/+ background does not lead to ectopic wings compared to controls.

Homozygous upd2Δ reduces tumor formation in the anterior midgut of Sox21a6 mutant flies.

upd2Δ further reduces the survival of upd3Δ flies compared to controls after oral infection with Erwinia carotovora carotovora 15.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (14)