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General Information
Symbol
Dmel\Abp1UAS.Tag:Myr(Src64B),GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0284214
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Abp1, which is tagged with a myristoylation motif (Tag:Myr(Src64B)) and with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP under the control of Scer\GAL4sca.PU results in a split microchaete phenotype. The phenotype ranges from short microchaetes with multiple splits (at least 4 visible tips) to microchaetes with only one or two splits either occurring laterally or within the upper third of the microchaete. Ultrastructural analysis indicates the that split structures have a common base, with one nerve cell extension in the centre. Split microchaetae are also reduced in length compared to wild type, while the diameter at the base and volume are normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Suppressed by
NOT suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Heterozygosity for either WASp1 or WASp3 does not suppress the split microchaete phenotype caused by expression of Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP under the control of Scer\GAL4sca.PU.

Co-expression of Arp2dsRNA.Scer\UAS.cUa strongly suppresses the split microchaete phenotype caused by expression of Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP under the control of Scer\GAL4sca.PU.

Heterozygosity for either SCARΔ37 or SCARk03107 suppresses the split microchaete phenotype caused by expression of Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP under the control of Scer\GAL4sca.PU.

Co-expression of HemScer\UAS.T:Myr-Src64B enhances the split microchaete phenotype caused by expression of Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP under the control of Scer\GAL4sca.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Abp1Scer\UAS.T:Myr-Src64B,T:Avic\GFP
Abp1UAS.Tag:Myr(Src64B),GFP
Name Synonyms
Secondary FlyBase IDs
    References (1)