UASt regulatory sequences drive expression of Hsap\LRRK2 carrying amino acid substitution G2385R tagged with Tag:FLAG at the N-terminus.
Flies expressing Hsap\LRRK2G2385R.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ple.PG do not show a progressive reduction in electroretinogram amplitude (there is no significant difference in the amplitude seen in 3 and 28 day old flies).
Expression of Hsap\LRRK2G2385R.Scer\UAS.T:Zzzz\FLAG in dendritic arborization (DA) neurons using Scer\GAL4109(2)80 engenders dendrite arborization defects as shown by the quantification of numbers of dendritic ends in the dorsal field of A6 segments in third instar larvae.