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General Information
Symbol
Dmel\POSHp327
Species
D. melanogaster
Name
FlyBase ID
FBal0284330
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

A 574 bp deletion resulting from the imprecise excision of P{EP}POSHEP1206, removes the ATG and N-terminal coding sequences of POSH. The flanking sequences to the deletion are : 5′-GCCACGAG-3′ & 3′-ACCTAAAC-5′.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of P{EP}POSHEP1206.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Approximately 7% of POSHp327/Df(2R)BSC45 embryos show a dorsal hole in the epidermis indicating the disruption of dorsal closure.

Approximately 6% of POSHk15815/POSHp327 embryos show a dorsal hole in the epidermis indicating the disruption of dorsal closure.

Approximately 5% of the homozygous POSHp327 embryos show a dorsal hole in the epidermis indicating the disruption of dorsal closure.

Approximately 2% of the homozygous POSHp327 embryos display head involution defects.

Approximately 6% of the homozygous POSHp327 embryos display germ-band retraction defects.

Approximately 87% of the homozygous POSHp327 embryos fail to hatch.

Approximately 3% of the POSHk15815/POSHp327 embryos display head involution defects.

Approximately 2% of the POSHk15815/POSHp327 embryos display germ-band retraction defects.

Only 24.5% of the POSHk15815/POSHp327 embryos hatch to the first instar larval stage.

Approximately 3% of the POSHp327/Df(2R)BSC45 embryos display head involution defects.

Approximately 4% of the POSHp327/Df(2R)BSC45 embryos display germ-band retraction defects.

64% of the POSHp327/Df(2R)BSC45 embryos hatch to the first instar larval stage.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

POSHp327/POSH[+] is a suppressor | partially of visible phenotype of Scer\GAL4GMR.PU, egrUAS.cIa

Phenotype Manifest In
Suppressor of
Statement
Reference

POSHp327/POSH[+] is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PU, egrUAS.cIa

Additional Comments
Genetic Interactions
Statement
Reference

Heterozygous POSHp327 can suppress the Scer\GAL4GMR.PU>egrScer\UAS.cIa eye phenotype by 37%.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
POSHp327
Name Synonyms
Secondary FlyBase IDs
    References (1)