The penetrance of the wing notching phenotype in CycGHR7/+;Df(1)N-54l9/+ double heterozygote adult flies is about the same as in the Df(1)N-54l9/+ single heterozygote but is decreased in CycGHR7/CycGHR7;Df(1)N-54l9/+ flies.
The net1 phenotype (ectopic veins, vein networking) can be enhanced by combination with CycGHR7 but also by combination with mutant alleles of unrelated factors ru1 or sp1 demonstrating high susceptibility of the net1 phenotype to perturbed genetic background.
The reduced body size and weight of CycGHR7 homozygote adults is fully rescued by combination with wdb mutant alleles in a heteroallelic state: the CycGHR7,wdbdw/CycGHR7,wdb14 flies have normal both body size and weight.
The ventralised eggshell phenotype seen in eggs derived from homozygous CycGHR7 females is suppressed in more than 90% of eggs if the females are also carrying either mei-W681/mei-W68k05603, lokp6/Df(2L)BSC258 or mei-41RT1/Df(1)BSC772.
The ventralised eggshell phenotype of eggs derived from spn-BBU CycGHR7/spn-B2 CycGHR7 double mutant females is enhanced compared to the defects seen in eggs from spn-BBU/spn-B2 and CycGHR7/CycGHR7 single mutant females.
Eggs derived from Brca256E/Brca2KO ; CycGHR7/CycGHR7 double mutant females have a mild eggshell patterning defect, which is not altered compared to the defect seen in eggs derived from Brca256E/Brca2KO single mutant females.
The reduced body weight of CycGHR7 homozygote adults can be ameliorated by ubiquitous ectopic expression of CycGScer\UAS.P\T.cNa under the Scer\GAL4da.PU driver, even though CycGScer\UAS.P\T.cNa;Scer\GAL4da.PU expression in a wild-type CycG background results in flies that are themselves slimmer than wild-type controls.