FB2025_01 , released February 20, 2025
Allele: Dmel\CycGUASp.cNa
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General Information
Symbol
Dmel\CycGUASp.cNa
Species
D. melanogaster
Name
FlyBase ID
FBal0284624
Feature type
allele
Associated gene
Dmel\CycG
Associated Insertion(s)
Carried in Construct
P{UASp-CycG.N}
Key Links
Transgenic product class
cDNA
(Nagel et al., 2012)
wild_type
(Nagel et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Nagel et al., 2012)
wild_type
(Nagel et al., 2012)
Mutagen
in vitro construct
(Nagel et al., 2012)
Progenitor genotype
Carried in construct
P{UASp-CycG.N}
Cytology
Description

UASp regulatory sequences drive expression of a CycG cDNA.

(Nagel et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
CycG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ubiquitous expression of CycGScer\UAS.P\T.cNa under the Scer\GAL4da.PU driver results in body weight loss in adult flies.

      (Fischer et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      CycGUASp.cNa/Scer\GAL4da.G32 rescues CycGHR7

      (Nagel et al., 2012)
      Partially rescues

      Scer\GAL4da.PU/CycGUASp.cNa partially rescues CycGHR7

      (Fischer et al., 2015)
      Comments

      The reduced body weight of CycGHR7 homozygote adults can be ameliorated by ubiquitous ectopic expression of CycGScer\UAS.P\T.cNa under the Scer\GAL4da.PU driver, even though CycGScer\UAS.P\T.cNa;Scer\GAL4da.PU expression in a wild-type CycG background results in flies that are themselves slimmer than wild-type controls.

      (Fischer et al., 2015)

      Expression of CycGScer\UAS.P\T.cNa under the control of Scer\GAL4da.G32 almost completely rescues the eggshell patterning defects of eggs derived from homozygous CycGHR7 females.

      (Nagel et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CycGScer\UAS.P\T.cNa
      CycGUASp.cNa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)