FB2021_01, released Feb 18, 2021

Allele: Dmel\robo1::robo2R1I1+2.UAS.Tag:HA,Tag:SS(wg)

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General Information
Symbol
Dmel\robo1::robo2R1I1+2.UAS.Tag:HA,Tag:SS(wg)
Species
D. melanogaster
Name
FlyBase ID
FBal0285368
Feature type
allele
Associated gene
robo1::robo2
Associated Insertion(s)
Carried in Construct
P{UAS-robo1::robo2.R1I1+2.HA}
Also Known As
UAS-Robo2R1I1+2
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Evans and Bashaw, 2010)
in vitro construct - coding region fusion
(Evans and Bashaw, 2010)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-robo1::robo2.R1I1+2.HA}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UASt regulatory sequences drive expression of a chimeric robo1::robo2 (composed of robo1 amino acid residues 56-252 and robo2 amino acid residues 281-1463) fused with a Tag:SS(wg) signal sequence and an N-terminal Tag:HA-tag.

      (Evans and Bashaw, 2010)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      robo1::robo2
      Tagged with
      Tag:HA
      Tag:SS(wg)
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of robo1::robo2R1I1+2.Scer\UAS.T:Ivir\HA1,T:SS-wg under the control of Scer\GAL4elav.PLu does not suppress the loss of commissure phenotype of homozygous commE39 embryos.

      (Evans et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      robo1::robo2R1I1+2.Scer\UAS.T:Ivir\HA1,T:SS-wg
      robo1::robo2R1I1+2.UAS.Tag:HA,Tag:SS(wg)
      robo::leaR1I1+2.Scer\UAS.T:Ivir\HA1,T:SS-wg
      Name Synonyms
      Secondary FlyBase IDs
        References (3)