Mutant eyes (generated using the "EGUF" method) show morphological defects (moderate rough eye phenotype) when animals are raised on medium containing 2mM caffeine.
MAGERZ/Df(3R)Antp1 animals show caffeine-dependent pupal lethality.
Dramatically increased apoptotic cell death is observed in the eye discs of MAGERZ/MAGEXL larvae after 12 hours exposure to caffeine.
MAGERZ/MAGEXL and MAGERZ/Df(3R)Antp1 animals show reduced survival after irradiation compared to controls.
BrdU incorporation in eye imaginal discs is abolished by hydroxyurea treatment in MAGERZ/MAGEXL larvae, as occurs in wild type.