Insertion in coding exon 2.
chemical sensitive (with Df(3L)BSC418)
chemical sensitive (with SMC5GS14577)
lethal | conditional
lethal | conditional (with Df(3L)BSC418)
lethal | conditional (with SMC5GS14577)
radiation sensitive (with SMC5GS14577)
Homozygous, Smc5GS3245/Smc5GS14577 and Smc5GS3245/Df(3L)BSC418 animals show caffeine-dependent lethality.
Homozygous and Smc5GS3245/Smc5GS14577 animals show reduced survival after irradiation compared to controls.
Excision of the insertion can revert the caffeine sensitive phenotype.