FB2025_01 , released February 20, 2025
Allele: Dmel\mei-41RNAi.UAS.cUa
Open Close
General Information
Symbol
Dmel\mei-41RNAi.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0285385
Feature type
allele
Associated gene
Dmel\mei-41
Associated Insertion(s)
Carried in Construct
P{UAS-mei-41.RNAi.U}
Key Links
Transgenic product class
RNAi_reagent
(Li et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Li et al., 2013)
Mutagen
in vitro construct
(Li et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-mei-41.RNAi.U}
Cytology
Description

UAS regulatory sequences drive expression of a mei-41 RNAi construct.

(Li et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mei-41
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APPT12.Aβ42.UAS.Tag:SS(nec)
      (Taylor et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      mei-41RNAi.UAS.cUa/Scer\GAL4ey.PU is an enhancer of visible | somatic clone | conditional phenotype of MAGERZ

      (Li et al., 2013)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      mei-41RNAi.UAS.cUa/Scer\GAL4ey.PU is an enhancer of eye | somatic clone | conditional phenotype of MAGERZ

      (Li et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of mei-41dsRNA.Scer\UAS.cUa under the control of Scer\GAL4ey.PU enhances the caffeine-dependent rough eye phenotype seen in homozygous MAGERZ eyes generated using the "EGUF" method.

      (Li et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mei-41RNAi.UAS.cUa
      mei-41dsRNA.Scer\UAS.cUa
      mei-41dsRNA.UAS.cUa
      Name Synonyms
      Secondary FlyBase IDs
        References (5)