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General Information
Symbol
Dmel\SPARCUASp.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Portela
FlyBase ID
FBal0285800
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-SPARC
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASp regulatory sequences drive expression of SPARC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of BM-40-SPARCScer\UAS.cPa under the control of Scer\GAL4GMR.PF significantly reduces the physiological peripheral photoreceptor cell death seen in control pupae.

Expression of BM-40-SPARCScer\UAS.cPa in photoreceptor neurons under the control of Scer\GAL4elav.PU suppresses the physiological cell death seen at the periphery of the pupal retina.

Expressing BM-40-SPARCScer\UAS.cPa under the control of Scer\GAL4GMR.PF (but restricting expression in the neuronal cells using Scer\GAL80elav.PU) does not suppress the physiological cell death seen at the periphery of the pupal retina.

Expressing BM-40-SPARCScer\UAS.cPa in primary pigment cells and cone cells under the control of Scer\GAL4wg.PU does not suppress the physiological cell death seen at the periphery of the pupal retina.

The overexpression of BM-40-SPARCScer\UAS.cPa in the genital disc using Scer\GAL4GMR.PF gives rise to wild-type terminalia.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

In wandering third instar larvae, the co-expression of SPARCScer\UAS.cPa suppresses the decreased relative area and apoptosis in somatic wing disc clones expressing wupAJF02172 under the control of Scer\GAL4Act.PU and the increased apoptosis in posterior wing disc compartments expressing wupAJF02172 under the control of Scer\GAL4en.PU.

Overexpression of BM-40-SPARCScer\UAS.cPa under the control of Scer\GAL4ap-md544 fails to suppress the increased apoptosis in apmd544/+ wing discs.

When BM-40-SPARCScer\UAS.cPa is activated specifically in the loser wild-type cells using Scer\GAL4αTub84B.PBb surrounded by dmαTub84B.PBb-expressing super-competitor cells, apoptosis is reduced and cell competition is prevented.

Co-expression of BM-40-SPARCScer\UAS.cPa fails to suppress the eye-size defect resulting from the ectopic expression of egrScer\UAS.cMa using Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
BM-40-SPARCScer\UAS.cPa
SPARCScer\UAS.cPa
SPARCUASp.cPa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Portela
Secondary FlyBase IDs
    References (5)