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General Information
Symbol
Dmel\Dop1R1UAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Liu
FlyBase ID
FBal0285851
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dDA1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS drives expression of Dop1R1 cDNA.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of Dop1R1Scer\UAS.cLa under the control of Scer\GAL4elav-C155 has no effect on viability.
Scer\GAL4c747-mediated expression of Dop1R1Scer\UAS.cLa results in significantly enhanced learning after aversive olfactory conditioning (flies trained to associate odors with an electric shock).
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of Dop1R1Scer\UAS.cLa and RdldsRNA.4-5.Scer\UAS does not result in further enhancement of learning after aversive olfactory conditioning compared to expression of either single transgene.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Expression of Dop1R1Scer\UAS.cLa in mostly the γ (with Scer\GAL4NP1131 or Scer\GAL4Tab2-201Y), but not the αβ (Scer\GAL4c739) or α'β' (Scer\GAL4c305a) mushroom body neurons, produces a significant restoration of memory performance and learning in Dop1R1f02676 mutants. Despite Dop1R1f02676 flies exhibiting an apparent olfactory acuity defect, restoration of olfaction through expression of Dop1R1Scer\UAS.cLa with the Scer\GAL4c305a and Scer\GAL4c739 drivers, does not correlate with wild-type learning ability.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Dop1R1Scer\UAS.cLa
Dop1R1UAS.cLa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Liu
Secondary FlyBase IDs
    References (5)