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General Information
Symbol
Dmel\eyaWT.UAS.Tag:Myr(v-Src)
Species
D. melanogaster
Name
FlyBase ID
FBal0287991
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulates expression of wild type eya with the Tag:Myr(v-Src) myristoylation sequence inserted at the N-terminus.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scer\GAL4dpp.blk1-mediated expression of eyaWT.Scer\UAS.T:Uuuu\Myr4 does not induce ectopic eyes.

Co-expression of eyaWT.Scer\UAS.T:SV40\nls2 and eyaWT.Scer\UAS.T:Uuuu\Myr4 via Scer\GAL4dpp.blk1 results in approximately two-fold more ectopic eye induction relative to expression of eyaWT.Scer\UAS.T:SV40\nls2 alone.

Scer\GAL4GMR.PU eyaWT.Scer\UAS.T:Uuuu\Myr4 eye/brain complexes show an average of 19.0 overshooting axon bundles per brain, compared to 8.4 in controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of AblGD1344 decreases the number of axon targeting defects in Scer\GAL4GMR.PU eyaWT.Scer\UAS.T:Uuuu\Myr4 eye/brain complexes from 19.0 to 8.7 axon bundles per brain.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Scer\GAL4dpp.blk1-mediated expression of eyaWT.Scer\UAS.T:Uuuu\Myr4 does not rescue the eyeless phenotype of eya2 animals.

Co-expression of eyaWT.Scer\UAS.T:SV40\nls2 and eyaWT.Scer\UAS.T:Uuuu\Myr4 via Scer\GAL4dpp.blk1 results in a more marked rescue of the eyeless phenotype of eya2 animals relative to expression of eyaWT.Scer\UAS.T:SV40\nls2 alone.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
eyaWT.Scer\UAS.T:Uuuu\Myr-v-Src
eyaWT.Scer\UAS.T:Uuuu\Myr4
eyaWT.UAS.Tag:Myr(v-Src)
Name Synonyms
Secondary FlyBase IDs
    References (2)