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General Information
Symbol
Dmel\eyaWT.UAS.NLS-MUT
Species
D. melanogaster
Name
FlyBase ID
FBal0287993
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulates expression of wild type eya fused to a non-functional mutant nuclear localization sequence (Tag:NLS(SV40-largeT) mutated from PPKKKRKV to PPKAARKV).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scer\GAL4dpp.blk1 eyaWT.Scer\UAS.T:SV40\nls2-MUT flies exhibit an average of ~35% frequency of ectopic eye induction (compared to 49% frequency when eyaWT.Scer\UAS is expressed).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Scer\GAL4dpp.blk1-mediated expression of eyaWT.Scer\UAS.T:SV40\nls2-MUT fully rescues the eyeless phenotype of eya2 animals.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
eyaWT.Scer\UAS.T:SV40\nls-largeT-MUT
eyaWT.Scer\UAS.T:SV40\nls2-MUT
eyaWT.UAS.NLS-MUT
eyaWT.UAS.T:SV40\nls-largeT-MUT
Name Synonyms
Secondary FlyBase IDs
    References (2)