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General Information
Symbol
Dmel\plumΔ2
Species
D. melanogaster
Name
FlyBase ID
FBal0288229
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Deletion resulting from FLP-catalyzed recombination using the FRT-containing transposons P{XP}CG5455d09586 and PBac{WH}plumf01589.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Scer\FRT-mediated recombination between the two progenitor insertions have resulted in the deletion of genomic sequence including part of plum.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The transverse nerve makes inappropriate connections at the neuromuscular junction in plumΔ2 larvae.

The frequency of improper, ectopic projections at the larval neuromuscular junction is increased compared to wild-type controls, with the majority of the ectopic connections being made by the transverse nerve.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of EcRB1.Scer\UAS under the control of Scer\GAL4elav.PU partially rescues the formation of ectopic connections at the neuromuscular junction in plumΔ1/plumΔ2 larvae.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

plumT:Avic\GFP,T:Ivir\HA1 completely rescues the formation of ectopic connections at the neuromuscular junction in plumΔ2 larvae.

Expression of plumScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PU (but not under the control of either Scer\GAL4Mef2.247 or Scer\GAL4repo.PU) rescues the formation of ectopic connections at the neuromuscular junction in plumΔ2 larvae.

Expression of plumΔIg1-3.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU rescues the formation of ectopic connections at the neuromuscular junction in plumΔ2 larvae.

Expression of plumΔIg4.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU fails to rescue the formation of ectopic connections at the neuromuscular junction in plumΔ2 larvae.

Expression of plumΔCyt.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU rescues the formation of ectopic connections at the neuromuscular junction in plumΔ2 larvae.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)