FB2021_01, released Feb 18, 2021

Allele: Dmel\SxlUAS.cRa

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General Information
Symbol
Dmel\SxlUAS.cRa
Species
D. melanogaster
Name
FlyBase ID
FBal0288259
Feature type
allele
Associated gene
Dmel\Sxl
Associated Insertion(s)
Carried in Construct
P{UAS-Sxl.R}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Ruiz et al., 2013)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-Sxl.R}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulatory sequences drive expression of Sxl.

      (Ruiz et al., 2013)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      Sxl
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Under control conditions, the adulthood-only expression of SxlUAS.cRa under the control of Scer\GAL4esg-NP7397 (and Gal80[ts], for the temporal regulation of expression) does not significantly affect the number of progenitor cells (intestinal stem cells/enteroblasts) or the mitotic index in the female or male adult posterior midgut, as compared to controls.

      (Hudry et al., 2016)

      Expression of SxlScer\UAS.cRa under the control of Scer\GAL4arm.PS results in full male lethality. Female viability is unaffected.

      Expression of SxlScer\UAS.cRa in a Sxlf1 mutant background results in full male lethality. Female viability is unaffected.

      (Ruiz et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SxlScer\UAS.cRa
      SxlUAS.cRa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)