Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} results in a dramatic increase in tumour and metastases incidence in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies: differentiated eye tissue is lost in 30% of the eye fields, and tumors are seen in 100% of the remaining eyes. These tumors include large patches of undifferentiated tissue.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to loss of retinal differentiation and to a 9% de novo tumor incidence in the remaining eye fields, with 6% of flies showing metastasis.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} increases ectopic proliferation in "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to the appearance of significant numbers of proliferating cells in the posterior region of third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in Scer\GAL4^ey.PH Dl^Scer\UAS.cDa third instar eye discs increases the proportion of undifferentiated to differentiated cells and, in some cases, results in lobes of proliferative and undifferentiated tissue.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} severely worsens the retinal patterning of "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs, to the extent that the morphogenetic furrow is difficult to discriminate.