FB2025_01 , released February 20, 2025
Allele: Dmel\Gprk2UAS.cFa
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General Information
Symbol
Dmel\Gprk2UAS.cFa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Fuse
FlyBase ID
FBal0290959
Feature type
allele
Associated gene
Dmel\Gprk2
Associated Insertion(s)
Carried in Construct
P{UAS-Gprk2.F}
Key Links
Transgenic product class
cDNA
(Fuse et al., 2013)
wild_type
(Fuse et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fuse et al., 2013)
wild_type
(Fuse et al., 2013)
Mutagen
in vitro construct
(Fuse et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Gprk2.F}
Cytology
Description

UASt regulatory sequences drive expression of part of the Gprk2 coding region (from EST clone RE34982).

(Fuse et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gprk2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Gprk2Scer\UAS.cFa under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 does not severely affect ventral furrow closure, although it partially inhibits apical constriction.

      (Fuse et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Gprk2Scer\UAS.cFa largely suppresses the gastrulation defects and semi-lethality seen when ctaScer\UAS.cFa is expressed under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16.

      Expression of Gprk2Scer\UAS.cFa does not suppress the embryonic defects seen when ctaQ303L.Scer\UAS is expressed under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16.

      (Fuse et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gprk2Scer\UAS.cFa
      Gprk2UAS.cFa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Fuse
      Secondary FlyBase IDs
        References (1)