FB2021_01, released Feb 18, 2021

Allele: Dmel\mir-277mut2.Ubi-p63E

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General Information
Symbol
Dmel\mir-277mut2.Ubi-p63E
Species
D. melanogaster
Name
FlyBase ID
FBal0291404
Feature type
allele
Associated gene
Dmel\mir-277
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-mir-277.mut2}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - site directed mutagenesis
(Esslinger et al., 2013)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      mir-277Ubi-p63E.PZ
      (Esslinger et al., 2013)
      Carried in construct
      P{Ubi-p63E-mir-277.mut2}
      Cytology
      Nature of the lesion
      Statement
      Reference

      Mutations have been introduced into the star-strand sequence of the mir-277 pre-miRNA hairpin, converting the hairpin into a perfectly base-paired dsRNA.

      (Esslinger et al., 2013)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      Ubi-p63E
      Encoded product / tool
      mir-277
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying mir-277mut2.Ubi-p63E have a substantially shortened lifespan on high sugar/high protein food medium.

      (Esslinger et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mir-277mut2.Ubi-p63E
      Name Synonyms
      Secondary FlyBase IDs
        References (1)