FB2025_01 , released February 20, 2025
Allele: Dmel\midF27-1
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General Information
Symbol
Dmel\midF27-1
Species
D. melanogaster
Name
FlyBase ID
FBal0291447
Feature type
allele
Associated gene
Dmel\mid
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Fregoso Lomas et al., 2013)
Mutagen
ethyl methanesulfonate
(Fregoso Lomas et al., 2013)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q98term.

(Fregoso Lomas et al., 2013)

Nucleotide substitution: ?294?.

(Fregoso Lomas et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:5,463,923..5,463,923 [+]
Nucleotide change:

C5463923T

Reported nucleotide change:

?294?

Amino acid change:

Q98term | mid-PA; Q98term | mid-PB

Reported amino acid change:

Q98term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Fregoso Lomas et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      midF27-1 mutant females produce eggshells with two dorsal appendages connected at their base by extra appendage material. Analysis of mutant mosaic egg epithelia reveals that this effect is cell autonomous and the eggshells produced by mosaic females exhibit nubs of extra appendage material in the corresponding region.

      (Fregoso Lomas et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      F271
      (Fregoso Lomas et al., 2013)
      midF27-1
      (Fregoso Lomas et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)