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General Information
Symbol
Dmel\elg1HMC03187
Species
D. melanogaster
Name
FlyBase ID
FBal0292364
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of a short inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of elg1HMC03187 RNAi under the control of the triple Scer\GAL4nos.PG,Scer\GAL4nos.UTR.T:Hsim\VP16, Scer\GAL4otu.T:Hsim\VP16 driver results in nurse cell endoreplication defects and underreplicated phenotype. Unlike controls, ovaries from elg1HMC03187 RNAi expressing females lack cells with ploidy levels of 128C-1024C, from the ploidy levels that surpass those found also in somatic cells they display a peak only at 64C and the stage 14 egg chambers lack dorsal appendages.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The underreplicated nurse cell phenotype characteristic for flies expressing elg1HMC03187 RNAi under the control of the triple Scer\GAL4nos.PG, Scer\GAL4nos.UTR.T:Hsim\VP16, Scer\GAL4otu.T:Hsim\VP16 driver is partially suppressed by co-expression of either enokHMS02165 RNAi or enokHMS02634 RNAi. The nurse cells are still underreplicated but the nuclei are relatively bigger and the cells display higher ploidy levels compared to females expressing elg1HMC03187 alone. enokHMS02634 RNAi also partially rescues the missing dorsal appendages phenotype observed in elg1HMC03187 RNAi expressing egg chambers.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG16838HMC03187
elg1HMC03187
Name Synonyms
Secondary FlyBase IDs
    References (2)