FlyBase Allele Report: Dmel\bsk[HMC03539]

General Information

Symbol

Dmel\bsk^HMC03539

Species

D. melanogaster

Name

FlyBase ID

FBal0292674

Feature type

allele

Associated gene

Dmel\bsk

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC03539}

Also Known As

HMC03539, bsk-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC03539}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC03539

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates hematologic cancer

modeled by mxc¹

(Takarada et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for bsk^HMC03539 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to bsk^HMC03539 males results in: 57% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

bsk^HMC03539/Scer\GAL4^He.PZ is a suppressor of abnormal cell migration | larval stage phenotype of mxc¹

(Takarada et al., 2023)

bsk^HMC03539/Scer\GAL4^He.PZ is a suppressor of abnormal cell adhesion | larval stage phenotype of mxc¹

(Takarada et al., 2023)

NOT Suppressor of

Statement

Reference

bsk^HMC03539, Scer\GAL4^repo is a non-suppressor of increased cell number | P-stage phenotype of PGRP-LE^UAS.Tag:FLAG, Scer\GAL4^repo

(Winkler et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

bsk^HMC03539/Scer\GAL4^He.PZ is a suppressor of larval circulating hemocyte | ectopic | increased number phenotype of mxc¹

(Takarada et al., 2023)

NOT Suppressor of

Statement

Reference

bsk^HMC03539, Scer\GAL4^repo is a non-suppressor of embryonic/larval plasmatocyte | increased number | P-stage phenotype of PGRP-LE^UAS.Tag:FLAG, Scer\GAL4^repo

(Winkler et al., 2021)

bsk^HMC03539, Scer\GAL4^repo is a non-suppressor of pupal central nervous system phenotype of PGRP-LE^UAS.Tag:FLAG, Scer\GAL4^repo

(Winkler et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

53310

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03539}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

basket^dsRNA

(Winkler et al., 2021)

bsk^HMC03539

jnk^RNAi

(Xie et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

Open Close