FlyBase Allele Report: Dmel\Xpd[HMJ21396]

General Information

Symbol

Dmel\Xpd^HMJ21396

Species

D. melanogaster

Name

FlyBase ID

FBal0293140

Feature type

allele

Associated gene

Dmel\Xpd

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ21396}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ21396}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ21396

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Xpd^HMJ21396/Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Scer\GAL4^GMR.PU, crb^{intra.UAS.Tag:MYC}

(Yeom et al., 2015)

Xpd^HMJ21396/Scer\GAL4^Bx-MS1096 is a suppressor of hyperplasia phenotype of Scer\GAL4^Bx-MS1096, crb^{intra.UAS.Tag:MYC}

(Yeom et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Xpd^HMJ21396/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, crb^{intra.UAS.Tag:MYC}

(Yeom et al., 2015)

Xpd^HMJ21396/Scer\GAL4^Bx-MS1096 is a suppressor of wing disc phenotype of Scer\GAL4^Bx-MS1096, crb^{intra.UAS.Tag:MYC}

(Yeom et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Xpd^HMJ21396 strongly suppresses the rough eye phenotype seen when crb^{intra.Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Xpd^HMJ21396 strongly suppresses the wing disc overproliferation phenotype seen when crb^{intra.Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^Bx-MS1096.

(Yeom et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

53992