FlyBase Allele Report: Dmel\wts[UAS.cYa]

General Information

Symbol

Dmel\wts^UAS.cYa

Species

D. melanogaster

Name

FlyBase ID

FBal0293735

Feature type

allele

Associated gene

Dmel\wts

Associated Insertion(s)

Carried in Construct

P{UAS-wts.Y}

Also Known As

UAS-wts

Key Links

Transgenic product class

wild_type

(Yin et al., 2013)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Yin et al., 2013)

Mutagen

in vitro construct

(Yin et al., 2013)

Progenitor genotype

Carried in construct

P{UAS-wts.Y}

Cytology

Description

UAS regulatory sequences drive expression of wts coding sequences.

(Yin et al., 2013)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

wts

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^Tub.PU

(Cao et al., 2014)

visible, with Scer\GAL4^Tub.PU

(Cao et al., 2014)

Phenotype Manifest In

eye, with Scer\GAL4^Tub.PU

(Cao et al., 2014)

wing, with Scer\GAL4^nub.PU

(Yin et al., 2013)

Detailed Description

Statement

Reference

Expression of wts^Scer\UAS.cYa under the control of Scer\GAL4^C587 has no apparent germarium phenotype.

(Li et al., 2015)

Overexpression of wts^Scer\UAS.cYa by the wing specific Scer\GAL4^nub.PU leads to a mild reduction in wing size.

(Yin et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^Tub.PU, wts^UAS.cYa has visible phenotype, enhanceable by Smurf[+]/Smurf^15C

(Cao et al., 2014)

Scer\GAL4^Tub.PU, wts^UAS.cYa has abnormal size phenotype, enhanceable by Smurf[+]/Smurf^15C

(Cao et al., 2014)

Enhancer of

Statement

Reference

Scer\GAL4^C587/wts^UAS.cYa is an enhancer of neoplasia | adult stage | female phenotype of Scer\GAL4^C587, ci^{RNAi.UASp.cLa}

(Li et al., 2015)

Suppressor of

Statement

Reference

wts^UAS.cYa, Scer\GAL4^Act5C.PI is a suppressor of some die during larval stage | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, emei¹

(Ma et al., 2020)

wts^UAS.cYa, Scer\GAL4^Act5C.PI is a suppressor of neoplasia | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, emei¹

(Ma et al., 2020)

wts^UAS.cYa, Scer\GAL4^Act5C.PI is a suppressor of neoplasia | somatic clone | larval stage phenotype of POSH^UAS.cSa, Ras85D^V12.UAS, Scer\GAL4^Act5C.PI

(Ma et al., 2020)

Other

Statement

Reference

Scer\GAL4^GMR.PU, hppy^UAS.cZa, wts^UAS.cYa has visible phenotype

(Zheng et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^Tub.PU, wts^UAS.cYa has eye phenotype, enhanceable by Smurf[+]/Smurf^15C

(Cao et al., 2014)

Enhancer of

Statement

Reference

Scer\GAL4^C587/wts^UAS.cYa is an enhancer of germarium phenotype of Scer\GAL4^C587, ci^{RNAi.UASp.cLa}

(Li et al., 2015)

Suppressor of

Statement

Reference

wts^UAS.cYa, Scer\GAL4^Act5C.PI is a suppressor of eye disc | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, emei¹

(Ma et al., 2020)

wts^UAS.cYa, Scer\GAL4^Act5C.PI is a suppressor of eye disc | somatic clone phenotype of POSH^UAS.cSa, Ras85D^V12.UAS, Scer\GAL4^Act5C.PI

(Ma et al., 2020)

Other

Statement

Reference

Scer\GAL4^GMR.PU, hppy^UAS.cZa, wts^UAS.cYa has eye phenotype

(Zheng et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Simultaneous expression of hpo^VDRC.cUa and wts^Scer\UAS.cYa under the control of Scer\GAL4^C587 has no apparent germarium phenotype.

The rather moderate tumorous germarium phenotype characteristic for adult female flies expressing ci^{dsRNA.shRNA.Scer\UAS.P\T} under the control of Scer\GAL4^C587 is strongly aggravated by co-expression of wts^Scer\UAS.cYa.

(Li et al., 2015)

Co-expression of hppy^Scer\UAS.cZa and wts^Scer\UAS.cYa under the control of Scer\GAL4^GMR.PU results in decreased eye size, compared to either transgene alone.

(Zheng et al., 2015)

Smurf^15C dominantly enhances the small and rough eye phenotype resulting from the expression of Scer\GAL4^tub.PU>wts^Scer\UAS.cYa.

(Cao et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

wts^Scer\UAS.cYa

wts^UAS.cYa

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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