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General Information
Symbol
Dmel\SxlM1,fΔ33
Species
D. melanogaster
Name
FlyBase ID
FBal0294059
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Deletion resulting from the imprecise excision of the progenitor insertion, which extends from +3410 to +7947 relative to the Sxl[[Pm]] transcription start site.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor P{lacW}SxlM1,fPw+c insertion results in a deletion of Sxl DNA from +3,410 to +7,947 (0 corresponds to the Sxl[[Pm]] transcription start site).

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Sxlf7,M1/SxlM1,fΔ33 females display masculinized external and internal somatic morphology and body size. The only hints of somatic femininity are a few small sixth-sternite bristles and about 25% fewer sexcomb teeth than seen in true males.

SxlM1,fΔ33 suppresses the dominant male-specific lethality of SxlM1.

SxlM1,fΔ33 supports wild-type oogenesis in homozygous mutant germline clones.

Sxlf7,M1 and SxlM1,fΔ33 fail to complement for female viability if exosed to 18[o]C during early embryogenesis or if exposed to 30[o] during the pupal period.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

traF.U2af50 feminizes Sxlf7,M1/SxlM1,fΔ33 mutants without increasing their size. Sxlf7,M1/SxlM1,fΔ33 ; traF.U2af50/+ females have large ovaries full of mature eggs, but they fail to lay.

Virgin Sxlf7,M1/SxlM1,fΔ33 ; traF.U2af50/+ females rescued by traF.U2af50 do lay eggs, some depositing nearly as many eggs as some of their mated sisters.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)