FB2025_01 , released February 20, 2025
Allele: Dmel\Rbpn-5Del1
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General Information
Symbol
Dmel\Rbpn-5Del1
Species
D. melanogaster
Name
FlyBase ID
FBal0294090
Feature type
allele
Associated gene
Dmel\Rbpn-5
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(2R)CG4030Del1
    Cytology
    Description

    Male recombination in flies carrying P{EPgy2}Rbpn-5EY21320 has resulted in a deletion encompassing Rbpn-5, CG4038 and CG34396.

    (Thomas and Strutt, 2014)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Rbpn-5Del1 mutants (Df(2R)CG4030Del1 homozygotes in which P{CH322-86L04-ΔCG4030} has been used to rescue the function of all the deleted genes except Rbpn-5) have an extended larval stage (approximately doubled compared to wild type at 25[o]C). The mutant larvae grow significantly larger than wild type, before dying shorter after pupation. The wing discs of the mutant larvae are variable in size, with many being no larger than normal. However, the epithelium is highly overgrown and folded in on itself. Cell size within the discs appears to be variable, with many of the cells being extremely enlarged.

        Homozygous Rbpn-5Del1 clones in the pupal wing are viable and appear similar to wild type (being neither obviously over- or under-proliferating).

        (Thomas and Strutt, 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Rbpn-5Del1
        Name Synonyms
        Secondary FlyBase IDs
          References (1)