FlyBase Allele Report: Hsap\HTT[128Q.1-336.UAS]

General Information

Symbol

Hsap\HTT^{128Q.1-336.UAS}

Species

H. sapiens

Name

FlyBase ID

FBal0294194

Feature type

allele

Associated gene

Hsap\HTT

Associated Insertion(s)

Carried in Construct

P{UAS-HTT.128Q.1-336}

Key Links

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Kaltenbach et al., 2007)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-HTT.128Q.1-336}

Cytology

Nature of the lesion

Statement

Reference

UASt regulatory sequences drive expression of the first 336 amino acids of Hsap\HTT, including a 128Q expansion in exon 1.

(Kaltenbach et al., 2007)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\HTT

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of Huntington's disease

CEA

(Stroedicke et al., 2015, Shirasaki et al., 2012, Kaltenbach et al., 2007)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of Huntington's disease

is exacerbated by M6^EY07032

(Kaltenbach et al., 2007)

is ameliorated by hts⁰¹¹⁰³

(Kaltenbach et al., 2007)

is exacerbated by Itpr^EY02522

(Kaltenbach et al., 2007)

is ameliorated by arm³

(Kaltenbach et al., 2007)

is ameliorated by arm^G0192

(Kaltenbach et al., 2007)

is ameliorated by Gpdh1^n1-5

(Kaltenbach et al., 2007)

is ameliorated by ND-PDSW^k10101

(Kaltenbach et al., 2007)

is exacerbated by zip⁰²⁹⁵⁷

(Kaltenbach et al., 2007)

is exacerbated by Gαi^EY10355

(Kaltenbach et al., 2007)

is ameliorated by Gαi^KG01907

(Kaltenbach et al., 2007)

is ameliorated by Itpr⁰⁵⁶¹⁶

(Kaltenbach et al., 2007)

is exacerbated by Dhc64C^4-19

(Kaltenbach et al., 2007)

is exacerbated by Asph^KG09881

(Kaltenbach et al., 2007)

is exacerbated by LamC^k11904

(Kaltenbach et al., 2007)

is ameliorated by αSnap^I1

(Kaltenbach et al., 2007)

is ameliorated by αSnap^M4

(Kaltenbach et al., 2007)

is ameliorated by faf^EP381

(Kaltenbach et al., 2007)

is ameliorated by porin^k05123

(Kaltenbach et al., 2007)

is exacerbated by CLIP-190^KG07837

(Kaltenbach et al., 2007)

is ameliorated by Khc⁸

(Kaltenbach et al., 2007)

is exacerbated by Pgi²

(Kaltenbach et al., 2007)

is ameliorated by Eip75B^BG02576

(Kaltenbach et al., 2007)

is ameliorated by pnut^XP

(Kaltenbach et al., 2007)

is ameliorated by Rpt1^43Ed-1

(Kaltenbach et al., 2007)

is exacerbated by zip^IIX62

(Kaltenbach et al., 2007)

is exacerbated by shot³

(Kaltenbach et al., 2007)

is exacerbated by Asph^ZCL1605

(Kaltenbach et al., 2007)

is ameliorated by Eip75B^KG09026

(Kaltenbach et al., 2007)

is exacerbated by Pgi^nNC1

(Kaltenbach et al., 2007)

is exacerbated by faf^BX4

(Kaltenbach et al., 2007)

is exacerbated by CAP^KG00308

(Kaltenbach et al., 2007)

is exacerbated by Syx1A^EP3215

(Kaltenbach et al., 2007)

is ameliorated by Ca-Ma2d^KG00260

(Kaltenbach et al., 2007)

is exacerbated by crol⁰⁴⁴¹⁸

(Kaltenbach et al., 2007)

is ameliorated by arm^G0234

(Kaltenbach et al., 2007)

is exacerbated by shot^65-2

(Kaltenbach et al., 2007)

is exacerbated by 14-3-3ζ^EY06147

(Kaltenbach et al., 2007)

is exacerbated by Unc-76^G0423a

(Kaltenbach et al., 2007)

is ameliorated by M6^BG00390

(Kaltenbach et al., 2007)

is exacerbated by Src42A^KG02515

(Kaltenbach et al., 2007)

is exacerbated by Unc-76^G0310

(Kaltenbach et al., 2007)

is ameliorated by αSnap^G8

(Kaltenbach et al., 2007)

is ameliorated by Mef2^KG01211a

(Kaltenbach et al., 2007)

is exacerbated by Lac^BG01462

(Kaltenbach et al., 2007)

is ameliorated by Mef2^X1

(Kaltenbach et al., 2007)

is exacerbated by Rpt1^EP2153

(Kaltenbach et al., 2007)

is ameliorated by Syx1A⁰⁶⁷³⁷

(Kaltenbach et al., 2007)

is ameliorated by Gpdh1^n1-4

(Kaltenbach et al., 2007)

is ameliorated by hts^k06121

(Kaltenbach et al., 2007)

is ameliorated by 14-3-3ε^j2B10

(Branco et al., 2008, Kaltenbach et al., 2007)

is ameliorated by hts^KG06777

(Kaltenbach et al., 2007)

is exacerbated by 14-3-3ε^UAS.cCa

(Branco et al., 2008, Kaltenbach et al., 2007)

is ameliorated by Chc¹

(Kaltenbach et al., 2007)

is exacerbated by CLIP-190^KG06490

(Kaltenbach et al., 2007)

is ameliorated by αSnap^P2

(Kaltenbach et al., 2007)

is ameliorated by porin^f03616

(Kaltenbach et al., 2007)

is exacerbated by Dhc64C^KG08838

(Kaltenbach et al., 2007)

is ameliorated by arm²

(Kaltenbach et al., 2007)

is ameliorated by Eip75B⁰⁷⁰⁴¹

(Kaltenbach et al., 2007)

is ameliorated by Khc^e02141

(Kaltenbach et al., 2007)

is exacerbated by CAP^BG02184

(Kaltenbach et al., 2007)

is exacerbated by Unc-76^G0333

(Kaltenbach et al., 2007)

is exacerbated by Lac^G00044

(Kaltenbach et al., 2007)

is ameliorated by Chc^BG02593a

(Kaltenbach et al., 2007)

is exacerbated by LamC^G00158

(Kaltenbach et al., 2007)

is exacerbated by Src42A^E1

(Kaltenbach et al., 2007)

is exacerbated by Src42A^k10108

(Kaltenbach et al., 2007)

is ameliorated by pnut⁰²⁵⁰²

(Kaltenbach et al., 2007)

is ameliorated by Eip75B^KG00139

(Kaltenbach et al., 2007)

is ameliorated by crol^EY08953

(Kaltenbach et al., 2007)

is ameliorated by pnut^KG00478

(Kaltenbach et al., 2007)

is ameliorated by Chc^G0438

(Kaltenbach et al., 2007)

is exacerbated by Ca-Ma2d^EY09750

(Kaltenbach et al., 2007)

is ameliorated by αSnap^M3

(Kaltenbach et al., 2007)

is ameliorated by Rpt1⁰⁵⁶⁴³

(Kaltenbach et al., 2007)

is ameliorated by Syx1A^Δ229

(Kaltenbach et al., 2007)

is exacerbated by 14-3-3ζ^EY03325

(Kaltenbach et al., 2007)

is exacerbated by CaMKII^GD9506

(Shirasaki et al., 2012)

is exacerbated by CCT1^c03987

(Shirasaki et al., 2012)

is ameliorated by Hsp60A^EY01572

(Shirasaki et al., 2012)

is ameliorated by Hsp83⁰⁸⁴⁴⁵

(Shirasaki et al., 2012)

is exacerbated by ND-30^GD5910

(Shirasaki et al., 2012)

is exacerbated by 14-3-3ε^GD4108

(Shirasaki et al., 2012)

is ameliorated by Gαi^EY10355

(Shirasaki et al., 2012)

is ameliorated by ND-30^EY03664

(Shirasaki et al., 2012)

is exacerbated by 14-3-3ε^ex4

(Shirasaki et al., 2012)

is ameliorated by Vps35^GD11710

(Shirasaki et al., 2012)

is ameliorated by Mpcp2⁰⁰⁵⁶⁴

(Shirasaki et al., 2012)

is ameliorated by CG45062^GD2154

(Shirasaki et al., 2012)

is ameliorated by Hsp60C^GD12177

(Shirasaki et al., 2012)

is exacerbated by nrv2^k13315

(Shirasaki et al., 2012)

is exacerbated by 14-3-3ζ^GD16467

(Shirasaki et al., 2012)

is ameliorated by Hsap\CRMP1^UAS.Tag:MYC

(Stroedicke et al., 2015)

is ameliorated by CRMP^EY04380

(Stroedicke et al., 2015)

is ameliorated by DnaJ-1^EP411

(Branco et al., 2008)

is exacerbated by eff⁸

(Branco et al., 2008)

is ameliorated by Hsap\STUB1^UAS.cAa

(Branco et al., 2008)

is exacerbated by skd^L7062

(Branco et al., 2008)

is exacerbated by tara^EP3463

(Branco et al., 2008)

is ameliorated by pum^bem

(Branco et al., 2008)

is exacerbated by cpo^EP3378

(Branco et al., 2008)

is ameliorated by Diap1^{UAS.cHa.Tag:MYC}

(Branco et al., 2008)

is ameliorated by Pi3K92E^UAS.Tag:MYC

(Branco et al., 2008)

is ameliorated by sov^KG00226

(Branco et al., 2008)

is exacerbated by Hsc70-3^K97S.UAS

(Branco et al., 2008)

is exacerbated by Hsap\STUB1^UAS.cAa

(Branco et al., 2008)

is exacerbated by Sin3A^dQ4

(Branco et al., 2008)

is exacerbated by Sirt1^EP2300

(Branco et al., 2008)

is exacerbated by pum^EP3461

(Branco et al., 2008)

is ameliorated by 14-3-3ε^ex4

(Branco et al., 2008)

is exacerbated by RhoGAPp190^EP1357

(Branco et al., 2008)

is exacerbated by Diap1⁴

(Branco et al., 2008)

is ameliorated by Akt^UAS.Tag:HA

(Branco et al., 2008)

is exacerbated by Akt⁰⁴²²⁶

(Branco et al., 2008)

is exacerbated by mub^EP3623

(Branco et al., 2008)

is exacerbated by vib^EP651

(Branco et al., 2008)

is exacerbated by vib^EP513

(Branco et al., 2008)

is exacerbated by sov^EP1438

(Branco et al., 2008)

is ameliorated by sol^GD8164

(Miller et al., 2010)

is ameliorated by SppL^GD284

(Miller et al., 2010)

is ameliorated by Spp^dsRNA.UAS

(Miller et al., 2010)

is ameliorated by CalpA^GD12275

(Miller et al., 2010)

is ameliorated by Mmp2^BG00958

(Miller et al., 2010)

is exacerbated by sol^EY02771

(Miller et al., 2010)

is ameliorated by SppL^EY06831

(Miller et al., 2010)

is ameliorated by gol^GD3528

(Miller et al., 2010)

is ameliorated by Mmp2⁰²³⁵³

(Miller et al., 2010)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

This allele represents a human variant implicated in disease.

(Kaltenbach et al., 2007)

HTT:p.Gln18[128]

(FlyBase curators, 2019-)

Variants Synonym(s)

HTT:p.Gln18[128Gln]

HTT, (CAG)n REPEAT EXPANSION

Associated human disease model(s)

Huntington disease

External database links

ClinVar: HTT_409

Comments concerning this variant

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

eye photoreceptor cell | adult stage, with Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

interommatidial bristle, with Scer\GAL4^GMR.PU

(Branco et al., 2008)

ommatidium, with Scer\GAL4^GMR.PU

(Branco et al., 2008)

retina, with Scer\GAL4^GMR.PU

(Branco et al., 2008, Kaltenbach et al., 2007)

Detailed Description

Statement

Reference

Expression of Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^GMR.PU results in photoreceptor degeneration, as compared to controls.

Expression of Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^elav.PU results in climbing defects, as compared to controls.

(Stroedicke et al., 2015)

Flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^elav.PU show a progressive decrease in climbing ability with age.

(Shirasaki et al., 2012, Miller et al., 2010)

Flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^GMR.PU show mild ommatidial disorganisation and bristle loss phenotypes. Severe disorganization, tissue loss and vacuolisation are seen in the retina. The phenotype becomes more severe with age.

Expression of Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^ey-OK107 results in the progressive formation of neuronal nuclear inclusions.

Flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^nrv2.PS exhibit progressive climbing defects.

(Branco et al., 2008)

Expression of Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^GMR.PU results in a degenerative retina phenotype which consists of shortening and detachment of the retina as well as the presence of vacuoles. Defects are also seen externally in the eye.

Flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^elav.PU have a shortened lifespan compared to controls and show a progressive decrease in climbing ability with age.

(Kaltenbach et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by nrv2^k13315

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by CCT1^c03987

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by 14-3-3ε^ex4

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by CaMKII^GD9506, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by ND-30^GD5910, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by 14-3-3ε^GD4108, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by 14-3-3ζ^GD16467, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by sol^EY02771, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^nrv2.PS has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by mub^EP3623, Scer\GAL4^nrv2.PS

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^nrv2.PS has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by vib^EP651, Scer\GAL4^nrv2.PS

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by M6^EY07032, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by 14-3-3ε^UAS.cCa, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Syx1A^EP3215, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Rpt1^EP2153, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Ca-Ma2d^EY09750, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by zip⁰²⁹⁵⁷

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by zip^IIX62

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by LamC^G00158

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by LamC^k11904

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by CLIP-190^KG07837

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Gαi^EY10355, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by CLIP-190^KG06490

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by shot³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by shot^65-2

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by CAP^BG02184

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by CAP^KG00308

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Lac^G00044

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Lac^BG01462

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Src42A^KG02515

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Src42A^k10108

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Src42A^E1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Itpr^EY02522, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Asph^ZCL1605

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Asph^KG09881

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Dhc64C^4-19

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Dhc64C^KG08838

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by faf^BX4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by crol⁰⁴⁴¹⁸

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Unc-76^G0310

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Unc-76^G0333

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Unc-76^G0423a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Pgi^nNC1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by 14-3-3ζ^EY06147, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by Pgi²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, enhanceable by 14-3-3ζ^EY03325, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Suppressed by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by CRMP^EY04380, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by Hsap\CRMP1^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by Hsap\CRMP1^UAS.Tag:MYC, Scer\GAL4^elav.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Hsp83⁰⁸⁴⁴⁵

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Hsp60A^EY01572

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Mpcp2⁰⁰⁵⁶⁴

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by CG45062^GD2154, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Gαi^EY10355, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Hsp60C^GD12177, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by ND-30^EY03664, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Vps35^GD11710, Scer\GAL4^elav.PU

(Shirasaki et al., 2012)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by Mmp2^BG00958

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by gol^GD3528, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by CalpA^GD12275, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by sol^GD8164, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by Spp^dsRNA.UAS, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by SppL^EY06831

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by SppL^GD284, Scer\GAL4^elav.PU

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by Mmp2⁰²³⁵³

(Miller et al., 2010)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by faf^EP381, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by arm^G0192

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by arm^G0234

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by arm²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by arm³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by M6^BG00390

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Khc^e02141

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Khc⁸

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by pnut^XP

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by pnut⁰²⁵⁰²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by pnut^KG00478

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by crol^EY08953, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Gαi^KG01907

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Itpr⁰⁵⁶¹⁶

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by 14-3-3ε^j2B10

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Chc¹

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Chc^G0438

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Chc^BG02593a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by αSnap^G8

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by αSnap^I1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by αSnap^M3

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by αSnap^M4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by hts⁰¹¹⁰³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by αSnap^P2

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Syx1A^Δ229

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Syx1A⁰⁶⁷³⁷

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Rpt1^43Ed-1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Rpt1⁰⁵⁶⁴³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Mef2^X1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Mef2^KG01211a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Eip75B^BG02576

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Eip75B^KG00139

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Eip75B^KG09026

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by hts^k06121

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Eip75B⁰⁷⁰⁴¹

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Ca-Ma2d^KG00260

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Gpdh1^n1-4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by Gpdh1^n1-5

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by ND-PDSW^k10101

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by porin^k05123

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by porin^f03616

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Syx1A^Δ229

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^elav.PU has short lived phenotype, suppressible by Syx1A^Δ229

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has visible phenotype, suppressible by hts^KG06777

(Kaltenbach et al., 2007)

NOT suppressed by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has abnormal neuroanatomy | adult stage phenotype, non-suppressible by Hsap\CRMP1^D408V.UAS, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by 14-3-3ε^UAS.cCa, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by Hsc70-3^K97S.UAS, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by eff⁸

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by Sin3A^dQ4

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by skd^L7062/skd[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by Sirt1^EP2300, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by tara^EP3463, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by cpo^EP3378, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by pum^EP3461, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by RhoGAPp190^EP1357, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by Diap1⁴/th[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by Akt1[+]/Akt⁰⁴²²⁶

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by mub^EP3623, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by vib^EP651, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by vib^EP513, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, enhanceable by sov^EP1438, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by M6^EY07032, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by 14-3-3ε^UAS.cCa, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Syx1A^EP3215, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Rpt1^EP2153, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Ca-Ma2d^EY09750, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by zip⁰²⁹⁵⁷

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Gαi^EY10355, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by zip^IIX62

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by LamC^G00158

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by LamC^k11904

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by CLIP-190^KG07837

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by CLIP-190^KG06490

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by shot³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by shot^65-2

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by CAP^BG02184

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by CAP^KG00308

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Lac^G00044

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Itpr^EY02522, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Lac^BG01462

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Src42A^KG02515

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Src42A^k10108

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Src42A^E1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Asph^ZCL1605

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Asph^KG09881

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Dhc64C^4-19

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Dhc64C^KG08838

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by faf^BX4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by crol⁰⁴⁴¹⁸

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by 14-3-3ζ^EY06147, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Unc-76^G0310

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Unc-76^G0333

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Unc-76^G0423a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Pgi^nNC1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Pgi²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by 14-3-3ζ^EY03325, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

NOT Enhanced by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by lncRNA:Hsrω^neo55/Hsromega[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by Sc2[+]/Sc2⁰⁵⁶³⁴

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by HDAC1⁰⁴⁵⁵⁶/Rpd3[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by CtBP[+]/CtBP⁰³⁴⁶³

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by GstS1[+]/GstS1⁰⁶²⁵³

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-enhanceable by mub⁰⁴⁰⁹³/mub[+]

(Branco et al., 2008)

Suppressed by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye photoreceptor cell | adult stage phenotype, suppressible | partially by CRMP^EY04380, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye photoreceptor cell | adult stage phenotype, suppressible | partially by Hsap\CRMP1^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by DnaJ-1^EP411, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by Hsap\STUB1^UAS.cAa, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by pum^bem/pum[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by 14-3-3ε^ex4/14-3-3epsilon[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by 14-3-3ε^j2B10/14-3-3epsilon[+]

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by Diap1^{UAS.cHa.Tag:MYC}, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by Akt^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by CG14438[+]/sov^KG00226

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, suppressible by Pi3K92E^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by faf^EP381, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by arm^G0192

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by arm^G0234

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by arm²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by arm³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by M6^BG00390

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by crol^EY08953, Scer\GAL4^GMR.PU

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Khc^e02141

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Khc⁸

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by pnut^XP

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by pnut⁰²⁵⁰²

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by pnut^KG00478

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Gαi^KG01907

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Itpr⁰⁵⁶¹⁶

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by 14-3-3ε^j2B10

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Chc¹

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Chc^G0438

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by hts⁰¹¹⁰³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Chc^BG02593a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by αSnap^G8

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by αSnap^I1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by αSnap^M3

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by αSnap^M4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by αSnap^P2

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Syx1A^Δ229

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Syx1A⁰⁶⁷³⁷

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Rpt1^43Ed-1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Rpt1⁰⁵⁶⁴³

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by hts^k06121

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Mef2^X1

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Mef2^KG01211a

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Eip75B^BG02576

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Eip75B^KG00139

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Eip75B^KG09026

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Eip75B⁰⁷⁰⁴¹

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Ca-Ma2d^KG00260

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Gpdh1^n1-4

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Gpdh1^n1-5

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by ND-PDSW^k10101

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by hts^KG06777

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by porin^k05123

(Kaltenbach et al., 2007)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye phenotype, suppressible by porin^f03616

(Kaltenbach et al., 2007)

NOT suppressed by

Statement

Reference

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has eye photoreceptor cell | adult stage phenotype, non-suppressible by Hsap\CRMP1^D408V.UAS, Scer\GAL4^GMR.PU

(Stroedicke et al., 2015)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-suppressible by ps[+]/ps³

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-suppressible by ps[+]/ps^j449

(Branco et al., 2008)

Hsap\HTT^{128Q.1-336.UAS}, Scer\GAL4^GMR.PU has retina phenotype, non-suppressible by Nup44A^EP2417, Scer\GAL4^GMR.PU

(Branco et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of CRMP^EY04380 or Hsap\CRMP1^{Scer\UAS.T:Hsap\MYC}, but not Hsap\CRMP1^{D408V.Scer\UAS}, partially suppresses the photoreceptor degeneration seen in flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^GMR.PU.

Co-expression of Hsap\CRMP1^{Scer\UAS.T:Hsap\MYC} partially suppresses the climbing defects seen in flies expressing Hsap\HTT^{128Q.1-336.Scer\UAS} under the control of Scer\GAL4^elav.PU.

(Stroedicke et al., 2015)

Expression of DnaJ-1^EP411 suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Hsc70-3^{K97S.Scer\UAS} enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

eff⁸ enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Hsap\STUB1^Scer\UAS.cAa suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Sin3A^dQ4 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of skd^L7062 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Sir2^EP2300 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of tara^EP3463 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of cpo^EP3378 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of pum^EP3461 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of pum^bem suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of 14-3-3ε^Scer\UAS.cCa enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of 14-3-3ε^ex4 suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of 14-3-3ε^j2B10 suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of RhoGAPp190^EP1357 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of th^{Scer\UAS.T:Hsap\MYC.cHa} suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of th⁴ enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of Hsrω^neo55 does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of Sc2⁰⁵⁶³⁴ does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of Rpd3⁰⁴⁵⁵⁶ does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of CtBP⁰³⁴⁶³ does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of ps³ does not suppress the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of ps^j449 does not suppress the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of GstS1⁰⁶²⁵³ does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Nup44A^EP2417 does not suppress the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Akt1^{Scer\UAS.T:Ivir\HA1} suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of Akt1⁰⁴²²⁶ enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of mub^EP3623 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of mub⁰⁴⁰⁹³ does not enhance the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of vib^EP651 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of vib^EP513 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of CG14438^EP1438 enhances the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

One copy of CG14438^KG00226 suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of Pi3K92E^{Scer\UAS.T:Hsap\MYC} suppresses the retinal phenotype seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PU.

Expression of mub^EP3623 enhances the climbing defects seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^nrv2.PS.

Expression of vib^EP651 enhances the climbing defects seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^nrv2.PS.

Expression of CG14438^EP1438 increases the number of neurons that contain nuclear inclusions seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^ey-OK107.

One copy of CG14438^KG00226 has no effect on the number of neurons that contain nuclear inclusions seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^ey-OK107.

Expression of Hsap\STUB1^Scer\UAS.cAa dramatically increases the number of neurons that contain nuclear inclusions seen when Hsap\HTT^{128Q.1-336.Scer\UAS} is expressed under the control of Scer\GAL4^ey-OK107.

(Branco et al., 2008)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\HTT^{128Q.1-336.Scer\UAS}

Hsap\HTT^{128Q.1-336.UAS}

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close