FlyBase Allele Report: Dmel\asf1[HMC03937]

General Information

Symbol

Dmel\asf1^HMC03937

Species

D. melanogaster

Name

FlyBase ID

FBal0294495

Feature type

allele

Associated gene

Dmel\asf1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC03937}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC03937}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC03937

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile, with Scer\GAL4^VP16.otu

(Yan and Perrimon, 2015)

lethal | female limited, with Scer\GAL4^dome-PG14

(Yan and Perrimon, 2015)

partially lethal - majority die, with Scer\GAL4^nub-AC-62

(Yan and Perrimon, 2015)

visible, with Scer\GAL4^bbg-C96

(Ellis et al., 2015)

visible, with Scer\GAL4^nub-AC-62

(Yan and Perrimon, 2015)

Phenotype Manifest In

wing, with Scer\GAL4^bbg-C96

(Ellis et al., 2015)

wing, with Scer\GAL4^nub-AC-62

(Yan and Perrimon, 2015)

Detailed Description

Statement

Reference

Expression of asf1^HMC03937 under the control of Scer\GAL4^bbg-C96 results in wing curling, but no evidence of increased cell death in the wing disc.

(Ellis et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^bbg-C96/asf1^HMC03937 is an enhancer of visible phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Scer\GAL4^bbg-C96/asf1^HMC03937 is an enhancer of increased cell death phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^bbg-C96/asf1^HMC03937 is an enhancer of wing phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Scer\GAL4^bbg-C96/asf1^HMC03937 is an enhancer of wing disc phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of asf1^HMC03937 enhances the wing nicking phenotype, and enhances the wing disc increased cell death along the dorsal-ventral wing margin of flies expressing dom^{dsRNA.Sym.Scer\UAS} under the control of Scer\GAL4^bbg-C96.

(Ellis et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

55250

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03937}attP40

Notes on Origin

Discoverer

Comments

Supplemental Dataset_S01.

(Yan and Perrimon, 2015)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

asf1^HMC03937

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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