Open Close
General Information
Symbol
Dmel\Atg17d130
Species
D. melanogaster
Name
FlyBase ID
FBal0294756
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:
A 8,196 bp deletion resulting from the imprecise excision of P{EPgy2}Atg17EY03045 removes all but 55 bases of the open reading frame of Atg17.
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Imprecise excision of the P{EPgy2}Atg17EY03045 progenitor insertion resulting in an 8196bp deletion that removes all but 55bp of the 4071 bp Atg17 coding sequence.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Homozygous Atg17d130 mutants are pharate adult lethal. Escapers are very rarely seen in Atg17d130 hemizygotes. Atg17d130 somatic clones exhibit severely impaired autophagosome formation. Autophagosomes and autolysosomes are absent from the fat bodies of starved Atg17d130 mutant larvae. Loss of Atg17 in Atg17d130 mutants blocks developmental autophagy in fat body cells and impairs programmed elimination of larval salivary glands during metamorphosis.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Atg17d130 completely suppresses the dmScer\UAS.cZa-induced overgrowth of fat cells.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
FIP200d130
FIP200[d130]
Name Synonyms
Secondary FlyBase IDs
    References (3)