FB2021_01, released Feb 18, 2021

Allele: Dmel\fruΔA

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General Information
Symbol
Dmel\fruΔA
Species
D. melanogaster
Name
FlyBase ID
FBal0295056
Feature type
allele
Associated gene
Dmel\fru
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-in gene targeting
(Neville et al., 2014)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Cytology
      Nature of the lesion
      Statement
      Reference

      Premature stop codons have been introduced into the Zn-finger containing "A" alternative 3' exon. A SalI site has also been introduced into the A exon.

      (Neville et al., 2014)
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      fruNP0021/fruΔC (but not fruNP0021/fruΔA or fruNP0021/fruΔB) MARCM clones (in Scer\GAL4fru-NP0021 neurons) fail to develop a male-specific mAL ipsilateral neurite.

      (Ito et al., 2016)

      Homozygous males show no decrease in viability.

      The muscle of Lawrence forms in fruΔA/Df(3R)fru4-40 males, as occurs in wild type.

      Compared to controls, fruΔA/Df(3R)fru4-40 males show no significant difference in latency to courtship of or courtship index towards females. Levels of copulation are also normal. The males show normal levels of fertility over a one-week observation period. fruΔA/Df(3R)fru4-40 males do not show chaining behaviour (forming male-male courtship chains).

      (Neville et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fruΔA
      (Zhang et al., 2020, Garner et al., 2018, Ito et al., 2016, Meissner et al., 2016, Neville et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)