FB2025_05 , released December 11, 2025
Allele: Dmel\enaS187A.UAS
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General Information
Symbol
Dmel\enaS187A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0295869
Feature type
allele
Associated gene
Dmel\ena
Associated Insertion(s)
Carried in Construct
P{UAS-ena.S187A}
Key Links
Transgenic product class
missense_variant
(Lucas et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Lucas et al., 2013)
Mutagen
in vitro construct
(Lucas et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-ena.S187A}
Cytology
Description

Amino acid replacement: S187A.

(Lucas et al., 2013)

UAS regulatory sequences drive expression of mutated ena coding sequences.

(Lucas et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ena
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of enaS187A.Scer\UAS, under the control of Scer\GAL4slbo.2.6 causes delayed border cell migration during stages 9 and 10, with prominent accumulation of F-actin throughout the border cell cluster.

      (Lucas et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased number of satellite boutons on neuromuscular junctions in third instar larvae expressing StripdsRNA.shRNA.Scer\UAS.9 under the control of Scer\GAL4RapGAP1-OK6 is suppressed by co-expression of enaS187A.Scer\UAS.

      (Sakuma et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      enaS187A.Scer\UAS
      enaS187A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)